What do systematic reviews say?

Ledermix (corticosteroid/antibiotic pulp-capping cement) vs Glycerrhetinic acid/antibiotic mixture

• Pulp management for caries in adults: maintaining pulp vitality 2007 · Cochrane All outcomes

  24 months
  Shovelton 1971 (Analysis 1.1): 275 teeth followed for 2 years (235 at 6 months, 160 at 12 months, 85 analysed at 24 months). Success rates 50% to 80%. Ledermix and calcium hydroxide had the highest success rates,…
  1 study · 275 participants
  GRADE not reported

Triple antibiotic paste (TAP) vs Abscess remedy (AR)

A single RCT found higher pulpotomy success with triple antibiotic paste than abscess remedy (100% vs 80%; statistically significant, P<0.05; not pooled; ungraded).

• Materials for pulpotomy in immature permanent teeth: a systematic review and meta-analysis. 2019 All outcomes

  3 to 24 months · Pediatric dental clinic (India)
  Single RCT (Eppa 2018, 3-arm; 20 TAP and 20 AR teeth): TAP 100% (20/20) vs abscess remedy 80% (16/20) clinical and radiographic success; difference statistically significant at 3, 6, 9, 12, 18 and 24 months (P<0.05);…
  1 study · 40 participants
  GRADE not reported

Glycerrhetinic acid/antibiotic mixture vs Calcium hydroxide (CH)

• Pulp management for caries in adults: maintaining pulp vitality 2007 · Cochrane All outcomes

  24 months
  Shovelton 1971 (Analysis 1.1): 275 teeth followed for 2 years (235 at 6 months, 160 at 12 months, 85 analysed at 24 months). Success rates 50% to 80%. Ledermix and calcium hydroxide had the highest success rates,…
  1 study · 275 participants
  GRADE not reported

Glycerrhetinic acid/antibiotic mixture vs Zinc oxide and eugenol (ZOE)

• Pulp management for caries in adults: maintaining pulp vitality 2007 · Cochrane All outcomes

  24 months
  Shovelton 1971 (Analysis 1.1): 275 teeth followed for 2 years (235 at 6 months, 160 at 12 months, 85 analysed at 24 months). Success rates 50% to 80%. Ledermix and calcium hydroxide had the highest success rates,…
  1 study · 275 participants
  GRADE not reported

Ledermix (corticosteroid/antibiotic pulp-capping cement) vs Calcium hydroxide (CH)

• Pulp management for caries in adults: maintaining pulp vitality 2007 · Cochrane All outcomes

  24 months
  Shovelton 1971 (Analysis 1.1): 275 teeth followed for 2 years (235 at 6 months, 160 at 12 months, 85 analysed at 24 months). Success rates 50% to 80%. Ledermix and calcium hydroxide had the highest success rates,…
  1 study · 275 participants
  GRADE not reported

Ledermix (corticosteroid/antibiotic pulp-capping cement) vs Zinc oxide and eugenol (ZOE)

• Pulp management for caries in adults: maintaining pulp vitality 2007 · Cochrane All outcomes

  24 months
  Shovelton 1971 (Analysis 1.1): 275 teeth followed for 2 years (235 at 6 months, 160 at 12 months, 85 analysed at 24 months). Success rates 50% to 80%. Ledermix and calcium hydroxide had the highest success rates,…
  1 study · 275 participants
  GRADE not reported

Fluoridated milk vs Non-fluoridated milk

The review found no eligible studies for this question.

• Fluoridated milk for preventing dental caries 2015 · Cochrane All outcomes
  No evidence found. (No information was reported by the included study.)
  0 studies
  No studies found

Mineral trioxide aggregate (MTA) pulpotomy dressing vs Triple antibiotic paste (TAP)

A single 3-arm RCT found no difference in pulpotomy success between MTA and triple antibiotic paste (both 100%; not pooled; ungraded).

• Materials for pulpotomy in immature permanent teeth: a systematic review and meta-analysis. 2019 All outcomes

  1 to 24 months · Pediatric dental clinic (India)
  Single RCT (Eppa 2018, 3-arm; 20 MTA and 20 TAP teeth): 100% clinical and radiographic success in both MTA and TAP at all follow-ups (1-24 months); no difference between groups; not pooled
  1 study · 40 participants
  GRADE not reported