Dysmenorrhoea: none or mild · patients with pain associated with endometriosis
Anti‐progestagen showed no clear difference in patient assessed efficacy none or mild painful periods (dysmenorrhoea) compared with other treatment (low certainty).
1 finding from 1 review
Objective assessment of efficacy at end of treatment (6 months) ‐ rAFS scores · patients with pain associated with endometriosis
1 finding from 1 review
Patient assessed efficacy painful periods visual analogue scale · patients with pain associated with endometriosis
1 finding from 1 review
Side effects ‐ seborrhoea · patients with pain associated with endometriosis
Anti‐progestagen may leads to higher side effects ‐ seborrhoea compared with other treatment (low certainty).
1 finding from 1 review
Side effects ‐ hirsutism · patients with pain associated with endometriosis
It is very uncertain whether anti‐progestagen changes side effects ‐ hirsutism compared with other treatment (very low certainty).
1 finding from 1 review
Side effects ‐ hot flushes · patients with pain associated with endometriosis
It is very uncertain whether anti‐progestagen changes side effects ‐ hot flushes compared with other treatment (very low certainty).
1 finding from 1 review
Side effects ‐ amenorrhoea · patients with pain associated with endometriosis
Anti‐progestagen may leads to lower side effects ‐ amenorrhoea compared with other treatment (low certainty).
1 finding from 1 review
AFS score · patients with pain associated with endometriosis
1 finding from 1 review
Adverse effect Breakthrough bleeding/spotting · patients with pain associated with endometriosis
Depot progestagen may leads to higher side effects ‐ breakthrough bleeding/spotting compared with other treatment (low certainty).
1 finding from 1 review
Side effects ‐ bloating · patients with pain associated with endometriosis
It is very uncertain whether depot progestagen changes side effects ‐ bloating compared with other treatment (very low certainty).
1 finding from 1 review
Local effects at injection site · patients with pain associated with endometriosis
Depot progestagen may leads to higher side effects ‐ injection site reaction compared with other treatment (low certainty).
1 finding from 1 review
Patient assessed efficacy ‐ pain · patients with pain associated with endometriosis
1 finding from 1 review
Objective efficacy at end of · patients with pain associated with endometriosis
1 finding from 1 review
Adverse effects: headache · patients with pain associated with endometriosis
Oral progestagens probably leads to lower side effects ‐ headache compared with other treatment (moderate certainty).
1 finding from 1 review
Side effects ‐ hot flushes · patients with pain associated with endometriosis
Oral progestagens may leads to lower side effects ‐ hot flushes compared with other treatment (low certainty).
1 finding from 1 review
Side effects ‐ genital bleeding · patients with pain associated with endometriosis
Oral progestagens may leads to higher side effects ‐ genital bleeding compared with other treatment (low certainty).
1 finding from 1 review
Side effects ‐ amenorrhoea · patients with pain associated with endometriosis
It is very uncertain whether oral progestagens changes side effects ‐ amenorrhoea compared with other treatment (very low certainty).
1 finding from 1 review
Sleep disorder · patients with pain associated with endometriosis
It is very uncertain whether oral progestagens changes sleep disorder compared with other treatment (very low certainty).
1 finding from 1 review
Patient assessed efficacy, sum of all symptoms · patients with pain associated with endometriosis
2 findings from 1 review
Adverse effects: acne · patients with pain associated with endometriosis
It is very uncertain whether progestagen changes side effects ‐ acne compared with placebo (very low certainty).
1 finding from 1 review