Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 2 · 40%Very low 0 · 0%Low 1 · 20%Moderate 2 · 40%High 0 · 0%

Early seizures (number of seizures) · people with traumatic head injuries

Anti‐epileptic drugs showed no clear difference in early seizure Counts of events compared with other anti‐epileptic drugs (low certainty).

1 finding from 1 review

Pharmacological treatments for preventing epilepsy following traumatic head injury 2015 · Cochrane Headline outcomes only
RR 0.66 [0.2, 2.12]
2 studies · 431 participants
Low

Late seizures (number of seizures) · people with traumatic head injuries

Anti‐epileptic drugs showed no clear difference in late seizure Counts of events compared with other anti‐epileptic drugs (moderate certainty).

1 finding from 1 review

Pharmacological treatments for preventing epilepsy following traumatic head injury 2015 · Cochrane Headline outcomes only
RR 0.77 [0.46, 1.3]
2 studies · 378 participants
Moderate

All‐cause mortality · people with traumatic head injuries

Anti‐epileptic drugs showed no clear difference in all‐cause mortality compared with other anti‐epileptic drugs (moderate certainty).

1 finding from 1 review

Pharmacological treatments for preventing epilepsy following traumatic head injury 2015 · Cochrane Headline outcomes only
RR 0.53 [0.3, 94]
2 studies · 431 participants
Moderate

Any serious adverse event of treatment · people with traumatic head injuries

1 finding from 1 review

Pharmacological treatments for preventing epilepsy following traumatic head injury 2015 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Seizures · people with traumatic head injuries

1 finding from 1 review

Pharmacological treatments for preventing epilepsy following traumatic head injury 2015 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported