Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Incontinence · Headline outcomes only

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 66.7%Low 1 · 33.3%Moderate 0 · 0%High 0 · 0%

Number of wet nights per week at the end of treatment ‐ Amitriptyline + desmopressin vs amitriptyline · children with nocturnal enuresis

1 finding from 1 review

Tricyclic and related drugs for nocturnal enuresis in children 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 28 participants
Very low

Number not achieving 14 consecutive dry nights at the end of treatment ‐ amitriptyline vs placebo · children with nocturnal enuresis

Tricyclics may leads to lower number not achieving 14 consecutive dry nights at the end of… compared with placebo (low certainty).

1 finding from 1 review

Tricyclic and related drugs for nocturnal enuresis in children 2016 · Cochrane Headline outcomes only
RR 0.83 [0.72, 0.97]
2 studies · 98 participants
Low

Mean number of wet nights a week · children with nocturnal enuresis

1 finding from 1 review

Tricyclic and related drugs for nocturnal enuresis in children 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
Very low