Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews · Pregnancy and Childbirth · Headline outcomes only

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No studies found 1 · 20%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 80%Moderate 0 · 0%High 0 · 0%

Paracetamol (single administration, any dose) vs placebo

Adequate pain relief as reported by women · women with perineal pain following childbirth

Paracetamol (single administration, any dose) may leads to higher adequate pain relief as reported by women compared with placebo (low certainty).

1 finding from 1 review

Paracetamol/acetaminophen (single administration) for perineal pain in the early postpartum period 2021 · Cochrane Headline outcomes only
RR 2.14 [1.59, 2.89]
10 studies · 1279 participants
Low

Paracetamol (single administration, any dose) vs placebo

Additional pain relief · women with perineal pain following childbirth

Paracetamol (single administration, any dose) may leads to lower additional pain relief compared with placebo (low certainty).

1 finding from 1 review

Paracetamol/acetaminophen (single administration) for perineal pain in the early postpartum period 2021 · Cochrane Headline outcomes only
RR 0.34 [0.21, 0.55]
8 studies · 1132 participants
Low

Paracetamol (single administration, any dose) vs placebo

Nausea · women with perineal pain following childbirth

Paracetamol (single administration, any dose) showed no clear difference in maternal drug adverse effects (nausea) compared with placebo (low certainty).

1 finding from 1 review

Paracetamol/acetaminophen (single administration) for perineal pain in the early postpartum period 2021 · Cochrane Headline outcomes only
RR 0.18 [0.01, 3.66]
1 study · 232 participants
Low

Paracetamol (single administration, any dose) vs placebo

Maternal drug adverse effects (sleepiness) · women with perineal pain following childbirth

Paracetamol (single administration, any dose) showed no clear difference in maternal drug adverse effects (sleepiness) compared with placebo (low certainty).

1 finding from 1 review

Paracetamol/acetaminophen (single administration) for perineal pain in the early postpartum period 2021 · Cochrane Headline outcomes only
RR 0.89 [0.18, 4.3]
1 study · 232 participants
Low

Paracetamol (single administration, any dose) vs placebo

Neonatal drug adverse effects · women with perineal pain following childbirth

The review found no eligible studies for this question.

1 finding from 1 review

Paracetamol/acetaminophen (single administration) for perineal pain in the early postpartum period 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found