Imiquimod 5% cream with tazarotene 0.1% gel vs Imiquimod 5% cream alone
- Interventions for melanoma in situ, including lentigo maligna 2014 · Cochrane Headline outcomes onlyno estimate extracted1 study · 88 participantsLow
Salt bath + UVB may leads to higher PASI‐75 (number of participants with event) compared with UVB alone (low certainty).
Salt bath + UVB showed no clear difference in treatment‐related adverse events requiring withdrawal (number of… compared with UVB alone (low certainty).
The review found no eligible studies for this question.
It is very uncertain whether topical active treatment in combination with moisturiser changes number of participants reporting an adverse event compared with topical active treatment alone (very low certainty).
Topical active treatment in combination with moisturiser may leads to lower number of participants who experienced a flare compared with topical active treatment alone (low certainty).
The review found no eligible studies for this question.
Flutamide 250 mg once to b.i.d. showed no clear difference in participant‐reported improvement of hirsutism 4‐point Likert scale compared with spironolactone 100 mg (low certainty).
Spironolactone 100 mg showed no clear difference in participant‐reported improvement of hirsutism 4‐point Likert scale compared with placebo (low certainty).
Spironolactone 100 mg showed no clear difference in proportion of participants who reported an adverse event compared with placebo (low certainty).
Ethinyl estradiol 35 μg + cyproterone acetate 2 mg showed no clear difference in proportion of participants who reported an adverse event compared with ethinyl estradiol 30 μg + desogestrel 0.15 mg (moderate certainty).
It is very uncertain whether finasteride 5 mg to 7.5 mg changes proportion of participants who reported an adverse event compared with placebo (very low certainty).
The review found no eligible studies for this question.
Finasteride 5 mg showed no clear difference in proportion of participants who reported an adverse event compared with spironolactone 100 mg (moderate certainty).
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