Incidence of T2DM (N) · people at increased risk for developing type 2 diabetes
Summary of findings: pioglitazone monotherapy may leads to lower incidence of T2DM (N) Diagnostic criteria: 3 studies applied the WHO… compared with placebo (low certainty).
1 finding from 1 review
Incidence of T2DM (N) · people at increased risk for developing type 2 diabetes
Summary of findings: pioglitazone monotherapy probably leads to lower incidence of T2DM (N) Diagnostic criteria: 9 studies applied the WHO… compared with no intervention (moderate certainty).
1 finding from 1 review
Metformin Diagnostic criteria: 2 studies applied the WHO 1999 criteria for 'prediabetes' (FPG > 6.1 mmol/L and < 7.0 mmol/L and/or a 2‐h glucose < 11.1 mmol/L after a 75 g OGTT; Chen 2007a; Zeng 2013) · people at increased risk for developing type 2 diabetes
Summary of findings: pioglitazone monotherapy showed no clear difference in metformin Diagnostic criteria: 2 studies applied the WHO 1999… compared with another pharmacological glucose‐lowering monotherapy (low certainty).
1 finding from 1 review
Acarbose Diagnostic criteria: 1 study applied the WHO 1999 criteria for prediabetes (FPG > 6.1 mmol/L and < 7.0 mmol/L and/or a 2‐h glucose < 11.1 mmol/L after a 75 g OGTT; Chen 2007a) · people at increased risk for developing type 2 diabetes
1 finding from 1 review
Repaglinide Diagnostic criteria: 1 study applied the ADA 2010 criteria (FPG ≥ 5.6 mmol/L and < 6.9 mmol/L and 2‐h glucose ≥ 7.8 mmol/L or < 11.0 mmol/L after a 75 g OGTT; Zhang 2007) · people at increased risk for developing type 2 diabetes
1 finding from 1 review
Thiazolidinediones Diagnostic criteria: 2 trials applied the WHO 1999 criteria (FPG ≥ 7.0 mmol/L and/or a 2‐hour glucose ≥ 11.1 mmol/L after a 75 g OGTT) (Jin 2009; Zeng 2013). No medical association recommended the cut‐off points applied in Maji ... · people at increased risk for developing type 2 diabetes
Summary of findings table for metformin showed no clear difference in thiazolidinediones Diagnostic criteria: 2 trials applied the WHO… compared with diet and exercise or another antidiabetic drug (low certainty).
1 finding from 1 review
Development of type 2 diabetes · people at increased risk for developing type 2 diabetes
It is very uncertain whether summary of findings table for metformin plus intensive diet and… changes incidence of type 2 diabetes mellitus (N) Diagnostic criteria: 2… compared with intensive diet and exercise (very low certainty).
1 finding from 1 review
Placebo or diet and exercise Diagnostic criteria: 3 trials applied the WHO 1985 criteria (FPG <7.8 mmol/L and 2‐hour glucose ≥7.8 mmol/L and <11.1 mmol/L after a 75 g OGTT) (Fang 2004; Li 1999; Lu 2002). 5 trials applied the WHO 1999 criteria (FPG... · people at increased risk for developing type 2 diabetes
Summary of findings table for metformin probably leads to lower placebo or diet and exercise Diagnostic criteria: 3 trials applied… compared with diet and exercise or another antidiabetic drug (moderate certainty).
1 finding from 1 review
Type 2 diabetes mellitus · people at increased risk for developing type 2 diabetes
1 finding from 1 review
Development of type 2 diabetes · people at increased risk for developing type 2 diabetes
Diet plus physical activity probably leads to lower incidence of type 2 diabetes mellitus Diagnostic criteria: 3 trials… compared with standard treatment (moderate certainty).
1 finding from 1 review
Intervention not reported
Proportion of women having their first OGTT after giving birth a) Postal reminder to woman and physician b) Postal reminder to woman c) Postal reminder to physician · women with previous gestational diabetes mellitus
The intervention may leads to higher proportion of women having their first OGTT after giving birth a)… (low certainty).
1 finding from 1 review
Intervention not reported
Proportion of women having a blood glucose test other than an OGTT after giving birth: fasting blood glucose a) Postal reminder to woman and physician b) Postal reminder to woman c) Postal reminder to physician · women with previous gestational diabetes mellitus
The intervention may leads to higher proportion of women having a blood glucose test other than an OGTT… (low certainty).
1 finding from 1 review