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Evidence found and GRADE certainty

4 questions · 4 findings · 2 reviews

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No studies found 0 · 0%GRADE not reported 1 · 25%Very low 0 · 0%Low 1 · 25%Moderate 2 · 50%High 0 · 0%

10% CPP-ACP paste vs no treatment

Arrest or reversal of noncavitated carious lesions on any coronal surface · Children and adults with noncavitated carious lesions on any coronal surface (primary and permanent teeth)

10% CPP-ACP paste may not differ from no treatment for arrest or reversal of any-coronal carious lesions (RR 1.03, 95% CI 0.9 to 1.18; low certainty).

1 finding from 1 review

10% CPP-ACP paste vs Fluoride varnish

Arrest or reversal of noncavitated carious lesions on any coronal surface · Children and adults with noncavitated carious lesions on any coronal surface (primary and permanent teeth)

10% CPP-ACP paste was probably less effective than 5% NaF varnish for arrest or reversal of any-coronal carious lesions (RR 0.48, 95% CI 0.38 to 0.6; moderate certainty).

1 finding from 1 review

1.23% APF gel vs CPP-ACP

Arrest or reversal of noncavitated carious lesions on any coronal surface · Children and adults with noncavitated carious lesions on any coronal surface (primary and permanent teeth)

1.23% APF gel was probably more effective than 10% CPP-ACP paste for arrest or reversal of any-coronal carious lesions (RR 2.19, 95% CI 1.83 to 2.61; moderate certainty).

1 finding from 1 review

SDF plus potassium iodide vs Split into two contrasts: (1) TCS paste (arrest 100%); (2) CPP-ACP (arrest 100%); SDF+KI arrest 54.8% at 24 months, p<.001

Caries arrest · Patients with early enamel carious lesions on permanent molars

SDF plus potassium iodide arrested 54.8% of early enamel lesions at 24 months; no pooled estimate or GRADE rating was reported.

1 finding from 1 review