Findings

What do systematic reviews say?

2,543 questions · 2,589 findings · 168 reviews · Schizophrenia

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No studies found 601 · 23.2%GRADE not reported 446 · 17.2%Very low 721 · 27.8%Low 505 · 19.5%Moderate 274 · 10.6%High 42 · 1.6%

Pericyazine vs Typical antipsychotics

Behaviour ‐ not measured · patients with schizophrenia

The review found no eligible studies for this question.

1 finding from 1 review

Pericyazine for schizophrenia 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Pericyazine vs Typical antipsychotics

Economic outcome ‐ not reported · patients with schizophrenia

The review found no eligible studies for this question.

1 finding from 1 review

Pericyazine for schizophrenia 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Pericyazine vs atypical antipsychotics

Global state: no improvement ‐ medium termAs defined in each study · patients with schizophrenia

It is very uncertain whether pericyazine changes global state ‐ not improved compared with atypical antipsychotic (very low certainty).

1 finding from 1 review

Pericyazine for schizophrenia 2014 · Cochrane Headline outcomes only
RR 0.97 [0.67, 1.42]
1 study · 93 participants
Very low

Pericyazine vs atypical antipsychotics

Adverse effects: any observed extrapyramidal symptoms ‐ short term (up to 6 months) · patients with schizophrenia

It is very uncertain whether pericyazine changes adverse Effects ‐ Extrapyramidal symptoms compared with atypical antipsychotic (very low certainty).

1 finding from 1 review

Pericyazine for schizophrenia 2014 · Cochrane Headline outcomes only
RR 2.69 [1.35, 5.36]
1 study · 93 participants
Very low

SULPIRIDE vs placebo

Global state: clinically significant response in global state ‐ by long term ‐ not measured · patients with schizophrenia

The review found no eligible studies for this question.

1 finding from 1 review

Sulpiride versus placebo for schizophrenia 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

SULPIRIDE vs placebo

Mental state: 2. Specific‐ Positive symptoms, total score‐ average endpoint scores (SADS‐C‐PD scale, lower = better) · patients with schizophrenia

1 finding from 1 review

Sulpiride versus placebo for schizophrenia 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Very low

SULPIRIDE vs placebo

Mental state: average score for negative symptoms ‐ by short term Manchester Scale, negative subset endpoint. Scale from: 0 to 20. · patients with schizophrenia

1 finding from 1 review

Sulpiride versus placebo for schizophrenia 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Very low

SULPIRIDE vs placebo

Mental state: average score for depressive and anxious symptoms ‐ by medium term ‐ not measured · patients with schizophrenia

The review found no eligible studies for this question.

1 finding from 1 review

Sulpiride versus placebo for schizophrenia 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

SULPIRIDE vs placebo

Quality of life: average score ‐ by long term ‐ not measured · patients with schizophrenia

The review found no eligible studies for this question.

1 finding from 1 review

Sulpiride versus placebo for schizophrenia 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

SULPIRIDE vs placebo

Severe adverse effects ‐ medium term ‐ not reported · patients with schizophrenia

The review found no eligible studies for this question.

1 finding from 1 review

Sulpiride versus placebo for schizophrenia 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

SULPIRIDE vs placebo

Safety assessments ‐ medium term ‐ not measured · patients with schizophrenia

The review found no eligible studies for this question.

1 finding from 1 review

Sulpiride versus placebo for schizophrenia 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Physical health monitoring vs No monitoring

Physical health ‐ failure to identify a disease state and provide appropriate treatment · people with severe mental disorders

1 finding from 1 review

Physical health care monitoring for people with serious mental illness 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Physical health monitoring vs No monitoring

Physical health ‐ failure to effectively manage a known disease state · people with severe mental disorders

1 finding from 1 review

Physical health care monitoring for people with serious mental illness 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Physical health monitoring vs No monitoring

Quality of life: Loss of activities of Daily Living (ADL) skills · people with severe mental disorders

1 finding from 1 review

Physical health care monitoring for people with serious mental illness 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Physical health monitoring vs No monitoring

Adverse effect: clinically important adverse effect of intervention ‐ as defined by individual studies · people with severe mental disorders

1 finding from 1 review

Physical health care monitoring for people with serious mental illness 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Physical health monitoring vs No monitoring

Adverse event ‐ death · people with severe mental disorders

1 finding from 1 review

Physical health care monitoring for people with serious mental illness 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Physical health monitoring vs No monitoring

Economic: Increased costs of health care · people with severe mental disorders

1 finding from 1 review

Physical health care monitoring for people with serious mental illness 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Physical health monitoring vs No monitoring

Social ‐ social isolation as a result of preventable incapacity · people with severe mental disorders

1 finding from 1 review

Physical health care monitoring for people with serious mental illness 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

PHYSICAL HEALTH ADVICE vs usual care

Physical health awareness ‐ not reported · people with severe mental disorders

The review found no eligible studies for this question.

1 finding from 1 review

General physical health advice for people with serious mental illness 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Health education vs HEALTH EMPOWERMENT EDUCATION

Adverse effects · people with serious mental illness

HEALTH EDUCATION led to lower adverse Effects compared with HEALTH EMPOWERMENT EDUCATION; GRADE not reported.

1 finding from 1 review

General physical health advice for people with serious mental illness 2014 · Cochrane Headline outcomes only
RR 0 [0, 0]
0 studies · 0 participants
GRADE not reported