Portland cement (PC) showed no clear difference in radiological failure compared with full strength formocresol (FC); GRADE not reported.
It is very uncertain whether total-etching 36% phosphoric acid + acetone-based total-etch adhesive changes radiological failure compared with non-rinse conditioner + acetone-based total-etch adhesive (very low certainty).
Mineral trioxide aggregate (MTA) showed no clear difference in radiological failure compared with mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl); GRADE not reported.
Mineral trioxide aggregate (MTA) showed no clear difference in radiological failure compared with ferric sulphate (FS) (low certainty).
Calcium hydroxide + sodium hypochlorite (NaOCl) showed no clear difference in radiological failure compared with calcium hydroxide (CH); GRADE not reported.
It is very uncertain whether self-etch adhesive + acetone-based total-etch adhesive changes radiological failure compared with total-etching 36% phosphoric acid + acetone-based total-etch adhesive (very low certainty).
Sodium hypochlorite (NaOCl) showed no clear difference in radiological failure compared with 1:5 diluted formocresol (FC); GRADE not reported.
It is very uncertain whether calcium hydroxide cement (Dycal) changes radiological failure compared with calcium sulphate hemihydrate (DentoGen) (very low certainty).
Biodentine showed no clear difference in clinical failure compared with propolis; GRADE not reported.
Vitapex (calcium hydroxide/iodoform) showed no clear difference in clinical failure compared with sealapex (eugenol-free calcium hydroxide); GRADE not reported.
Zinc oxide and eugenol (ZOE) showed no clear difference in radiological failure compared with formocresol (FC); GRADE not reported.
Diode laser showed no clear difference in radiological failure compared with electrosurgery (low certainty).
It is very uncertain whether non-rinse conditioner + acetone-based total-etch adhesive changes radiological failure compared with acetone-based total-etch adhesive (very low certainty).
Sealapex (eugenol-free calcium hydroxide) showed no clear difference in clinical failure compared with zinc oxide and eugenol (ZOE); GRADE not reported.
Beta‐blockers showed no clear difference in total mortality compared with renin‐angiotensin system inhibitors (moderate certainty).
Beta‐blockers showed no clear difference in total cardiovascular disease compared with renin‐angiotensin system inhibitors (low certainty).
Beta‐blockers probably leads to higher total stroke compared with renin‐angiotensin system inhibitors (moderate certainty).
Beta‐blockers showed no clear difference in total coronary heart disease compared with renin‐angiotensin system inhibitors (low certainty).
Beta‐blockers probably leads to higher withdrawal due to adverse effect compared with renin‐angiotensin system inhibitors (moderate certainty).