Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,710 questions · 14,842 findings · 1,394 reviews

No studies found 2,880 · 19.4%GRADE not reported 1,413 · 9.5%Very low 3,103 · 20.9%Low 3,870 · 26.1%Moderate 2,663 · 17.9%High 913 · 6.2%

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Topical repellents vs placebo or no treatment

Malaria case and infection incidence together ( · people living in malaria‐endemic areas

Topical repellents may leads to lower malaria case and infection incidence together ( compared with placebo or no treatment (low certainty).

1 finding from 1 review

Topical anesthetics vs placebo or no intervention

Episodes of apnea · lumbar puncture in newborn infants

It is very uncertain whether topical anesthetics changes apnea: occurrence of one or more episodes№ of LPs: 100(1 quasi‐RCT) compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Light vibrational forces (LVF) vs Conventional orthodontic appliance treatment

Rate of orthodontic tooth movement with removable orthodontic aligners · Adolescents and adults with malocclusion undergoing orthodontic treatment with fixed or removable appliances

Light vibrational forces (LVF) showed no clear difference in rate of orthodontic tooth movement with removable orthodontic aligners compared with conventional orthodontic appliance treatment (placebo or no adjunct); GRADE not reported.

1 finding from 1 review

Light vibrational forces (LVF) vs Conventional orthodontic appliance treatment

Orthodontic tooth movement (OTM) during alignment stage · Adolescents and adults with malocclusion undergoing orthodontic treatment with fixed or removable appliances

Light vibrational forces (LVF) showed no clear difference in orthodontic tooth movement (OTM) during alignment stage (reduction… compared with conventional orthodontic appliance treatment (placebo or no adjunct) (low certainty).

1 finding from 1 review