Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,776 questions · 7,311 findings · 959 reviews · Headline outcomes only

No studies found 1,498 · 20.5%GRADE not reported 303 · 4.1%Very low 1,839 · 25.2%Low 1,991 · 27.2%Moderate 1,277 · 17.5%High 403 · 5.5%

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SSRI antidepressants vs tricyclic antidepressants (TCAs)

Drop‐out Objective · Adults with mental disorders in low‐ and middle‐income countries

It is very uncertain whether SSRI antidepressants changes drop‐outs (12 weeks) compared with TCA (very low certainty).

1 finding from 1 review

Metformin vs placebo

Fasting blood glucose (mg/dL) · Adults with mental disorders in low‐ and middle‐income countries
2 findings from 1 review

Intervention not reported

PUL (UroLift) (mixed estimate) · men with moderate to severe lower urinary symptoms due to benign prostatic hyperplasia Interventions: minimally invasive treatments.…

It is very uncertain whether the intervention changes PUL (UroLift) (mixed estimate) (very low certainty).

1 finding from 1 review

Intervention not reported

PAE (mixed estimate) · men with moderate to severe lower urinary symptoms due to benign prostatic hyperplasia Interventions: minimally invasive treatments.…

It is very uncertain whether the intervention changes PAE (mixed estimate) (very low certainty).

1 finding from 1 review