Number of (minor aphthous) oral ulcers · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
Colchicine (0.5 mg per day for 3 months) showed no clear difference in number of aphthous ulcers at completion compared with prednisolone (5 mg per day for 3 months); GRADE not reported.
1 finding from 1 review
Pain (on movement and on palpation of the affected TMJ) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
1 finding from 1 review
Data for pain on movement or pain on palpation of the affected TMJ (both at 1 week and 3 months) could not be extracted, as they are described as percentages of an unclear total number. Narratively, diclofenac sodium…
1 study
GRADE not reported
Adverse effects · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
Colchicine was associated with statistically significantly more adverse effects than prednisolone (nine participants reporting adverse effects on colchicine versus two on prednisolone).
1 study · 34 participants
GRADE not reported
Adverse effects · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
Pain reduction (participant-reported symptoms) · People with erosive oral lichen planus
1 finding from 1 review
Recurrence · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
Colchicine (0.5 mg per day for 3 months) showed no clear difference in recurrence during treatment period compared with prednisolone (5 mg per day for 3 months); GRADE not reported.
1 finding from 1 review
Partial response (partial or complete response) · People with erosive oral lichen planus
Topical clobetasol propionate 0.025% showed no clear difference in partial response (partial or complete response) compared with topical clobetasol propionate 0.05%; GRADE not reported.
1 finding from 1 review
Aesthetics evaluated by the dentist (any validated aesthetic index) · Partially edentulous patients receiving posterior mandibular implants
Subepithelial connective tissue graft (palate) at implant placement led to lower aesthetics (pink aesthetic score, PES) evaluated by dentist compared with no augmentation; GRADE not reported.
1 finding from 1 review
Reduction in target/mean lesion size · People with erosive oral lichen planus
Topical tacrolimus 0.1% ointment showed no clear difference in reduction in target/mean lesion size compared with topical clobetasol propionate 0.05% ointment; GRADE not reported.
1 finding from 1 review
Alveolar bone loss · Partially edentulous patients (mandible) receiving FDPs; split-mouth, 10-year
1 finding from 1 review
Open TMJ surgery (arthroplasty / total joint replacement)
Outcome not reported · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
The review found no eligible studies for this question.
1 finding from 1 review
Patient satisfaction · Partially edentulous patients with a distal-extension RDP (minor connector); cross-over
1 finding from 1 review
The tilting-type RDP significantly outscored the functional and sanitary designs for patient satisfaction; within-patient SDs not given, data narrative only
1 study · 25 participants
GRADE not reported
Abutment mobility · Partially edentulous patients treated with a mandibular RDP (major connector)
RDP with lingual plate major connector led to lower abutment tooth mobility (Periotest) at 30 months compared with RDP with sublingual bar major connector; GRADE not reported.
1 finding from 1 review
Side effects · People with erosive oral lichen planus
1 finding from 1 review
Total sugar intake frequency (mean number of intakes per day) · Adults with frequent sugar intake harbouring Streptococcus mutans and Streptococcus sobrinus in saliva (14 dental technical students and 6…
1 finding from 1 review
Table 5, total mean (SD) intakes/day: intervention 9.5 (1.9) baseline, 1.6 (1.4) at 3 weeks, 1.8 (1.5) at 6 weeks, 7.8 (3.5) at 12 weeks; control 7.2 (2.6), 7.1 (3.7), 6.5 (4.2), 6.7 (2.2). Significant reduction versus…
1 study · 20 participants
GRADE not reported
Effectiveness · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
Total number of new lesions over 2-month treatment period · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
Prednisone (oral, commencing 25 mg with phased dose reduction over 2… showed no clear difference in total number of new lesions over 2-month treatment period compared with montelukast (leukotriene receptor antagonist); GRADE not reported.
1 finding from 1 review
Adverse effects · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
There was a greater percentage of treatment interruptions in the colchicine group due to gastrointestinal adverse effects (Fisher's exact test P=0.009). The review noted potential evidence of harm at a dose of 1.5 mg…
1 study · 43 participants
GRADE not reported
Patients with increased abutment tooth mobility · Partially edentulous patients treated with a distal-extension RDP
Altered-cast technique RDP showed no clear difference in patients with increased abutment tooth mobility compared with one-piece cast RDP; GRADE not reported.
1 finding from 1 review
Adverse effects · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review