Antimicrobial resistance · Adults with aggressive periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Probing pocket depth · Adults with periodontitis (chronic and aggressive)
Amoxicillin + metronidazole + SRP led to lower probing pocket depth compared with SRP; GRADE not reported.
3 findings from 1 review
MD -0.47 [-0.68, -0.26]
6 studies · 215 participants
GRADE not reported
MD -0.18 [-0.33, -0.04]
15 studies · 562 participants
GRADE not reported
MD -0.30 [-0.42, -0.18]
2 studies · 389 participants
Very low
Percentage of bleeding on probing (BOP) · Adults with periodontitis (chronic and aggressive)
Azithromycin + SRP led to lower percentage of bleeding on probing (BOP) compared with SRP; GRADE not reported.
3 findings from 1 review
MD -3.32 [-6.23, -0.42]
6 studies · 228 participants
GRADE not reported
MD -1.28 [-4.32, 1.76]
2 studies · 110 participants
Very low
MD -3.18 [-7.01, 0.65]
6 studies · 216 participants
GRADE not reported
Postoperative pain (mean) · Adults with mandibular third molars requiring removal
Triangular flap led to lower postoperative pain (mean) compared with envelope flap; GRADE not reported.
1 finding from 1 review
Probing pocket depth · Adults with aggressive periodontitis
Doxycycline + SRP showed no clear difference in probing pocket depth compared with metronidazole + SRP; GRADE not reported.
3 findings from 1 review
MD 0.38 [0.00, 0.76]
3 studies · 75 participants
GRADE not reported
MD 1.00 [0.30, 1.70]
1 study · 27 participants
Very low
MD -0.16 [-0.56, 0.24]
2 studies · 49 participants
GRADE not reported
Probing pocket depth · Adults with aggressive periodontitis
Clindamycin + SRP showed no clear difference in probing pocket depth compared with metronidazole + SRP; GRADE not reported.
3 findings from 1 review
MD -0.14 [-0.82, 0.54]
1 study · 26 participants
GRADE not reported
MD -0.10 [-0.79, 0.59]
1 study · 26 participants
GRADE not reported
MD 0.20 [-0.38, 0.78]
1 study · 26 participants
Very low
Temporary altered tongue sensation · Adults with mandibular third molars requiring removal
Lingual split with chisel showed no clear difference in temporary altered tongue sensation compared with lingual split with bur; GRADE not reported.
1 finding from 1 review
Percentage of bleeding on probing (BOP) · Adults with chronic periodontitis
It is very uncertain whether amoxicillin + clavulanate + SRP changes percentage of bleeding on probing (BOP) compared with SRP (very low certainty).
3 findings from 1 review
MD 0.00 [-0.09, 0.09]
1 study · 21 participants
Very low
MD -0.10 [-0.19, -0.01]
1 study · 21 participants
GRADE not reported
MD -0.10 [-0.19, -0.01]
1 study · 21 participants
GRADE not reported
Clinical attachment level (CAL) · Adults with aggressive periodontitis
Amoxicillin + metronidazole + SRP showed no clear difference in clinical attachment level (CAL) compared with clarithromycin + SRP; GRADE not reported.
2 findings from 1 review
Probing pocket depth · Adults with chronic periodontitis
Amoxicillin + clavulanate + SRP showed no clear difference in probing pocket depth compared with SRP; GRADE not reported.
3 findings from 1 review
MD 0.00 [-0.19, 0.19]
1 study · 21 participants
GRADE not reported
MD 0.10 [-0.17, 0.37]
1 study · 21 participants
Very low
MD 0.20 [-0.02, 0.42]
1 study · 21 participants
GRADE not reported
Adverse events · Adults with aggressive periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Percentage of bleeding on probing (BOP) · Adults with aggressive periodontitis
Doxycycline + SRP showed no clear difference in percentage of bleeding on probing (BOP) compared with metronidazole + SRP; GRADE not reported.
3 findings from 1 review
MD -0.05 [-0.22, 0.12]
1 study · 22 participants
GRADE not reported
Included studies have not reported this outcome
Studies not reported
No studies found
MD -0.07 [-0.29, 0.15]
1 study · 22 participants
GRADE not reported
Percentage of bleeding on probing (BOP) · Adults with periodontitis (chronic and aggressive)
It is very uncertain whether metronidazole + SRP changes percentage of bleeding on probing (BOP) compared with SRP (very low certainty).
3 findings from 1 review
MD -6.90 [-22.10, 8.30]
1 study · 22 participants
Very low
MD -9.00 [-16.59, -1.40]
4 studies · 108 participants
GRADE not reported
MD -4.62 [-18.83, 9.58]
2 studies · 45 participants
GRADE not reported
Wound dehiscence · Adults with mandibular third molars requiring removal
Triangular flap led to lower adverse effects (wound dehiscence) compared with envelope flap; GRADE not reported.
1 finding from 1 review
Temporary altered tongue, chin, or lip sensation · Adults with mandibular third molars requiring removal
Lingual nerve retractor (subperiosteal or Free's) led to higher temporary altered tongue, chin, or lip sensation compared with no retractor; GRADE not reported.
1 finding from 1 review
Probing pocket depth · Adults with aggressive periodontitis
The review found no eligible studies for this question.
2 findings from 1 review
Clinical attachment level (CAL) · Adults with aggressive periodontitis
It is very uncertain whether clindamycin + SRP changes clinical attachment level (CAL) compared with doxycycline + SRP (very low certainty).
3 findings from 1 review
MD -0.90 [-1.62, -0.18]
1 study · 23 participants
Very low
MD -0.40 [-1.15, 0.35]
1 study · 23 participants
GRADE not reported
MD 0.50 [-0.26, 1.26]
1 study · 23 participants
GRADE not reported
Postoperative pain · Adults with mandibular third molars requiring removal
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Patient-reported quality of life changes · Adults with aggressive periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Maximal mouth opening (interincisal distance) · Adults with mandibular third molars requiring removal
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found