Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,016 questions · 2,067 findings · 222 reviews · Headline outcomes only

No studies found 471 · 22.8%GRADE not reported 108 · 5.2%Very low 570 · 27.6%Low 458 · 22.2%Moderate 363 · 17.6%High 97 · 4.7%

Intervention not reported

Co‐amoxiclav or cefotaxime versus placebo (percutaneous endoscopic gastrostomy) · surgical patients

It is very uncertain whether the intervention changes co‐amoxiclav or cefotaxime versus placebo (percutaneous endoscopic… (very low certainty).

1 finding from 1 review

Intervention not reported

One dose of cefotiam or cefmetazol versus four doses of cefotiam or cefmetazol (elective surgery for colon cancer) · surgical patients

It is very uncertain whether the intervention changes one dose of cefotiam or cefmetazol versus four doses of cefotiam or… (very low certainty).

1 finding from 1 review

Intervention not reported

Pefloxacin versus cefazolin and oxacillin (tibial fracture requiring external fixation) · surgical patients

It is very uncertain whether the intervention changes pefloxacin versus cefazolin and oxacillin (tibial fracture requiring… (very low certainty).

1 finding from 1 review

Intervention not reported

Vancomycin and cefazolin versus daptomycin and cefazolin (vascular surgery) · surgical patients

It is very uncertain whether the intervention changes vancomycin and cefazolin versus daptomycin and cefazolin (vascular… (very low certainty).

1 finding from 1 review

Intervention not reported

Vancomycin versus cefuroxime (coronary artery bypass graft without valvular disease) · surgical patients

It is very uncertain whether the intervention changes vancomycin versus cefuroxime (coronary artery bypass graft without… (very low certainty).

1 finding from 1 review

Intervention not reported

One dose of cefotiam or cefmetazol versus four doses of cefotiam or cefmetazol (elective surgery for colon cancer) · surgical patients

It is very uncertain whether the intervention changes one dose of cefotiam or cefmetazol versus four doses of cefotiam or… (very low certainty).

1 finding from 1 review

Intervention not reported

Kanamycin, erythromycin and cefotiam versus cefotiam (surgery for colorectal diseases) · surgical patients

It is very uncertain whether the intervention changes kanamycin, erythromycin and cefotiam versus cefotiam (surgery for… (very low certainty).

1 finding from 1 review

Intervention not reported

Vancomycin versus cefuroxime (coronary artery bypass graft without valvular disease) · surgical patients

It is very uncertain whether the intervention changes vancomycin versus cefuroxime (coronary artery bypass graft without… (very low certainty).

1 finding from 1 review

Intervention not reported

Moxifloxacin versus piperacillin/tazobactam followed by amoxycillin/clavulanate · patients with MRSA‐infected non surgical wounds

It is very uncertain whether the intervention changes moxifloxacin versus piperacillin/tazobactam followed by… (very low certainty).

1 finding from 1 review

Summary of findings: quinolone prophylaxis vs TMP‐SMZ prophylaxis

All cause‐mortality · cancer patients with afebrile neutropenia following chemotherapy

Summary of findings: quinolone prophylaxis probably leads to higher all cause‐mortality compared with TMP‐SMZ prophylaxis (moderate certainty).

1 finding from 1 review