Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,720 questions · 15,377 findings · 900 reviews

No studies found 3,865 · 25.1%GRADE not reported 2,291 · 14.9%Very low 3,875 · 25.2%Low 3,287 · 21.4%Moderate 1,681 · 10.9%High 378 · 2.5%

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High vs low dose pegylated interferon alpha‐2a or alpha‐2b

PEG interferon alpha‐2a · patients on HD with HCV infection

High showed no clear difference in PEG interferon alpha‐2a compared with low dose pegylated interferon alpha‐2a or alpha‐2b (low certainty).

4 findings from 1 review
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High vs low dose pegylated interferon alpha‐2a or alpha‐2b

PEG interferon (alpha‐2b) · patients on HD with HCV infection

High showed no clear difference in PEG interferon alpha‐2b compared with low dose pegylated interferon alpha‐2a or alpha‐2b (low certainty).

2 findings from 1 review

High vs low dose pegylated interferon alpha‐2a or alpha‐2b

PEG interferon (combined) · patients on HD with HCV infection

High showed no clear difference in PEG interferon (combined) compared with low dose pegylated interferon alpha‐2a or alpha‐2b (moderate certainty).

3 findings from 1 review