Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,532 questions · 2,642 findings · 483 reviews · Headline outcomes only

No studies found 534 · 20.2%GRADE not reported 82 · 3.1%Very low 641 · 24.3%Low 807 · 30.5%Moderate 472 · 17.9%High 106 · 4%

Band ligation vs no intervention or a sham procedure

All‐cause mortality · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment

It is very uncertain whether band ligation changes all‐cause mortality compared with sham or no intervention (very low certainty).

1 finding from 1 review

Band ligation vs no intervention or a sham procedure

Serious adverse events Idiopathic thrombocytopaenic purpura · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment

It is very uncertain whether band ligation changes serious adverse events Idiopathic thrombocytopaenic purpura compared with sham or no intervention (very low certainty).

1 finding from 1 review

Band ligation vs no intervention or a sham procedure

Health‐related quality of life · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment

The review found no eligible studies for this question.

1 finding from 1 review

Band ligation vs no intervention or a sham procedure

Oesophageal variceal bleeding · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment

It is very uncertain whether band ligation changes oesophageal variceal bleeding compared with sham or no intervention (very low certainty).

1 finding from 1 review

Band ligation vs no intervention or a sham procedure

Adverse events considered non‐serious · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment

The review found no eligible studies for this question.

1 finding from 1 review

Risk‐based vs extensive on‐site monitoring

Combined outcome of proportion of participants with major or critical monitoring findings · clinical trials in all fields of health care

Risk‐based showed no clear difference in combined outcome of proportion of participants with major or… compared with extensive on‐site monitoring (moderate certainty).

1 finding from 1 review

Intervention not reported

Change in the visual field (short term) · participants with glaucoma or intraocular hypertension
1 finding from 1 review

Intervention not reported

Reduction in IOP (short term) · participants with glaucoma or intraocular hypertension
1 finding from 1 review
  • Acupuncture for glaucoma 2020 · Cochrane Headline outcomes only
    no estimate extracted
    3 studies · 137 participants
    Very low

Intervention not reported

Change in visual acuity (short term) · participants with glaucoma or intraocular hypertension
1 finding from 1 review