Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

2,556 questions · 2,794 findings · 119 reviews · Oral Health

No studies found 489 · 17.5%GRADE not reported 1,719 · 61.5%Very low 399 · 14.3%Low 128 · 4.6%Moderate 58 · 2.1%High 1 · 0%

Pentoxifylline vs placebo

Pain, number of ulcers, ulcer-free days and ulcer size · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
  • Systemic interventions for recurrent aphthous stomatitis (mouth ulcers) 2012 · Cochrane All outcomes
    60 days (plus 60-day follow-up)
    A single trial at high risk of bias compared pentoxifylline 400 mg three times daily (n=14) with placebo (n=12). No statistically significant differences were reported for pain, number of ulcers and ulcer-free days at…
    1 study · 26 participants
    GRADE not reported

Er:YAG laser surface debridement before bone augmentation vs Plastic curettes plus saline solution before bone augmentation

Change in probing pocket depth (PPD) · People with at least one dental implant affected by perimplantitis

Er:YAG laser surface debridement before bone augmentation showed no clear difference in change in probing pocket depth (PPD reduction) compared with plastic curettes plus saline solution before bone augmentation; GRADE not reported.

1 finding from 1 review

Colchicine (0.5 mg three times per day) vs placebo

Complete remission (no further aphthous episodes to 6 months) · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
  • The trial by de Abreu 2009 (high risk of bias) also assessed colchicine (n=23) versus placebo (n=20). The number with no further aphthous episodes at 6 months was not significantly different from placebo (Fisher's…
    1 study · 43 participants
    GRADE not reported

Er:YAG laser surface debridement before bone augmentation vs Plastic curettes plus saline solution before bone augmentation

Change in soft tissue recession (REC) · People with at least one dental implant affected by perimplantitis

Er:YAG laser surface debridement before bone augmentation showed no clear difference in change in soft tissue recession (REC) compared with plastic curettes plus saline solution before bone augmentation; GRADE not reported.

1 finding from 1 review

Aloe vera gel vs placebo

Side effects · People with erosive oral lichen planus
1 finding from 1 review
  • Table 3 (Side-effects). Choonhakarn 2008: no serious side-effects; 2 participants receiving aloe vera gel reported stinging and mild itching at lesions within the first week, symptoms spontaneously disappeared with…
    1 study · 45 participants
    GRADE not reported

Individualised homeopathic medicine (two doses over 24 hours) vs placebo

Pain free by end of study (day 6) · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

Individualised homeopathic medicine (two doses over 24 hours) led to higher pain free by end of study (day 6) compared with placebo; GRADE not reported.

1 finding from 1 review

Er:YAG laser debridement vs Manual debridement plus chlorhexidine irrigation/gel

Complications and side effects · People with at least one dental implant affected by perimplantitis

Er:YAG laser debridement led to lower complications and side effects compared with manual debridement plus chlorhexidine irrigation/gel; GRADE not reported.

1 finding from 1 review

Betamethasone oral mini-pulse therapy vs Topical triamcinolone acetonide paste

Investigator‐ or physician‐rated global assessment of disease severity · People with erosive oral lichen planus

Betamethasone oral mini-pulse therapy led to higher physician Global Assessment (clinical severity, 0-12 score) compared with topical triamcinolone acetonide 0.1% paste; GRADE not reported.

1 finding from 1 review

One-to-one advice on sugar restriction: detailed information on the sugar content of foods, with instruction to refrain from sugar-containing foods between meals and to reduce sugar in main meals (6-week sugar restriction) vs No advice on sugar restriction

Sugar intake frequency between meals (mean number of intakes per day) · Adults with frequent sugar intake harbouring Streptococcus mutans and Streptococcus sobrinus in saliva (14 dental technical students and 6…
1 finding from 1 review

Glucosamine sulfate (oral) vs ibuprofen

Pain-free maximum jaw opening (mm), change from baseline · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria

Glucosamine sulfate (oral) showed no clear difference in pain-free maximum jaw opening (mm), change from baseline compared with ibuprofen (oral); GRADE not reported.

1 finding from 1 review