Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,536 questions · 2,637 findings · 315 reviews

No studies found 608 · 23.1%GRADE not reported 488 · 18.5%Very low 688 · 26.1%Low 540 · 20.5%Moderate 249 · 9.4%High 64 · 2.4%

Intervention not reported

RT vs supportive care only · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option

The intervention probably leads to lower RT vs supportive care only (moderate certainty).

1 finding from 1 review

Intervention not reported

Hypofractionated RT vs standard RT (60Gy/30 fractions) · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option

The intervention led to lower hypofractionated RT vs standard RT (60Gy/30 fractions); GRADE not reported.

1 finding from 1 review

Intervention not reported

TMZ vs RT · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option

The intervention showed no clear difference in TMZ vs RT (low certainty).

1 finding from 1 review

Intervention not reported

CRT vs RT · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option

The intervention leads to lower CRT vs RT (high certainty).

1 finding from 1 review

Intervention not reported

BEV_CRT vs CRT · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option

The intervention showed no clear difference in BEV_CRT vs CRT (low certainty).

1 finding from 1 review

Intervention not reported

BEV_RT vs RT · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option

The intervention probably leads to lower BEV_RT vs RT (moderate certainty).

1 finding from 1 review

Intervention not reported

RIN_CRT vs CRT · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

TTF_AC vs CRT · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

IRI_BEV_RT vs CRT · elderly people with newly diagnosed glioblastoma Interventions: one treatment option Comparison: an alternative treatment option

The review found no eligible studies for this question.

1 finding from 1 review

Enamel matrix derivative (EMD; Emdogain) vs placebo or control

Aesthetics · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…

Enamel matrix derivative (EMD; Emdogain) showed no clear difference in aesthetics compared with placebo or control (same surgical or non-surgical intervention… (low certainty).

1 finding from 1 review

Enamel matrix derivative (EMD; Emdogain) vs placebo or control

Change in gingival recession (REC) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…

Enamel matrix derivative (EMD; Emdogain) showed no clear difference in change in gingival recession (REC) compared with placebo or control (same surgical or non-surgical intervention… (low certainty).

1 finding from 1 review

Enamel matrix derivative (EMD; Emdogain) vs placebo or control

Change in probing pocket depth (PPD) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…

Enamel matrix derivative (EMD; Emdogain) may leads to higher change in probing pocket depth (PPD) compared with placebo or control (same surgical or non-surgical intervention… (low certainty).

1 finding from 1 review

Enamel matrix derivative (EMD; Emdogain) vs placebo or control

Change in probing attachment level (PAL) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…

Enamel matrix derivative (EMD; Emdogain) may leads to higher change in probing attachment level (PAL) compared with placebo or control (same surgical or non-surgical intervention… (low certainty).

1 finding from 1 review

Enamel matrix derivative (EMD; Emdogain) vs placebo or control

Tooth loss · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
1 finding from 1 review