Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,749 questions · 14,261 findings · 832 reviews

No studies found 3,655 · 25.6%GRADE not reported 2,111 · 14.8%Very low 3,646 · 25.6%Low 3,028 · 21.2%Moderate 1,501 · 10.5%High 320 · 2.2%

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Summary of findings table ‐ High sodium dialysate vs standard sodium dialysate

Dialysis dysequilibrium syndrome · patients requiring haemodialysis

It is very uncertain whether summary of findings table ‐ High sodium dialysate changes dialysis dysequilibrium syndrome compared with standard sodium dialysate (very low certainty).

1 finding from 1 review

Summary of findings table ‐ High sodium dialysate vs standard sodium dialysate

Severe dialysis dysequilibrium syndrome · patients requiring haemodialysis

It is very uncertain whether summary of findings table ‐ High sodium dialysate changes severe dialysis dysequilibrium syndrome compared with standard sodium dialysate (very low certainty).

1 finding from 1 review

Occlusal splint vs Another occlusal splint with a different mechanism of action

Range of mandibular motion · People with temporomandibular disorders (TMD)

Occlusal splint showed no clear difference in range of mandibular motion compared with another occlusal splint with a different mechanism of action; GRADE not reported.

1 finding from 1 review

Intralesional betamethasone vs placebo

Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
1 finding from 1 review
  • Goel 2015 (3-arm: intralesional betamethasone vs lycopene vs placebo, 90 per arm): appeared to show increased interincisal distance in both intervention groups vs placebo, but only between-group differences with no…
    1 study · 180 participants
    GRADE not reported