Findings

What do systematic reviews say?

4,678 questions · 4,859 findings · 283 reviews

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No studies found 1,225 · 25.2%GRADE not reported 215 · 4.4%Very low 1,241 · 25.5%Low 1,210 · 24.9%Moderate 776 · 16%High 192 · 4%

Summary of findings: Higher bladder volume vs lower bladder volume

Diarrhoea (grade 2+) · Men undergoing RT for prostate cancer

The review found no eligible studies for this question.

1 finding from 1 review

Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: Higher bladder volume vs lower bladder volume

QoL · Men undergoing RT for prostate cancer

The review found no eligible studies for this question.

1 finding from 1 review

Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: liposomal bupivacaine vs placebo

Cumulative pain score from the end of operation (0 hours) to 72 hours (NRS 0 to 10) · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 189 participants
Very low

Summary of findings: liposomal bupivacaine vs bupivacaine

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 134 participants
Very low

Summary of findings: liposomal bupivacaine vs bupivacaine

Time to first postoperative opioid dose over initial 72 hours · aged 18 years and older undergoing elective surgery at any surgical site

The review found no eligible studies for this question.

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: liposomal bupivacaine vs bupivacaine

Total postoperative opioid consumption over first 72 hours · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 134 participants
Very low

Summary of findings: liposomal bupivacaine vs bupivacaine

Percentage of participants not requiring postoperative opioids over initial 72 hours · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 134 participants
Very low

Summary of findings: liposomal bupivacaine vs bupivacaine

Incidence of adverse events within 30 days of surgery · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 583 participants
Moderate

Summary of findings: liposomal bupivacaine vs placebo

Serious adverse events · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 382 participants
Low

Summary of findings: liposomal bupivacaine vs placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · aged 18 years and older undergoing elective surgery at any surgical site

The review found no eligible studies for this question.

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: liposomal bupivacaine vs placebo

Time to first postoperative opioid dose over initial 72 hours · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 382 participants
Low

Summary of findings: liposomal bupivacaine vs placebo

Total postoperative opioid consumption over first 72 hours · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 189 participants
Very low

Summary of findings: liposomal bupivacaine vs placebo

Percentage of participants not requiring postoperative opioids over initial 72 hours · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 382 participants
Very low

Summary of findings: liposomal bupivacaine vs placebo

Incidence of adverse events within 30 days of surgery · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 382 participants
Low

Summary of findings: liposomal bupivacaine vs bupivacaine

Cumulative pain score from the end of operation (0 hours) to 72 hours (NRS 0 to 10) · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 379 participants
Very low

Summary of findings: liposomal bupivacaine vs bupivacaine

Serious adverse events · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 583 participants
Moderate

Summary of findings: partial salpingectomy vs clip

Major morbidity: total · women requesting postpartum or interval sterilisation

1 finding from 1 review

Techniques for the interruption of tubal patency for female sterilisation 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 2198 participants
GRADE not reported

Summary of findings: partial salpingectomy vs clip

Minor morbidity: total · women requesting postpartum or interval sterilisation

Summary of findings: partial salpingectomy showed no clear difference in minor morbidity: total compared with clip (low certainty).

1 finding from 1 review

Techniques for the interruption of tubal patency for female sterilisation 2016 · Cochrane Headline outcomes only
OR 7.39 [0.46, 119.01]
1 study · 193 participants
Low

Summary of findings: partial salpingectomy vs clip

Technical failures · women requesting postpartum or interval sterilisation

Summary of findings: partial salpingectomy probably leads to lower technical failures compared with clip (moderate certainty).

1 finding from 1 review

Techniques for the interruption of tubal patency for female sterilisation 2016 · Cochrane Headline outcomes only
OR 0.18 [0.08, 0.4]
1 study · 2198 participants
Moderate

Summary of findings: partial salpingectomy vs clip

Failure rate: total (12 months) · women requesting postpartum or interval sterilisation

Summary of findings: partial salpingectomy probably leads to lower failure rate: total (12 months) compared with clip (moderate certainty).

1 finding from 1 review

Techniques for the interruption of tubal patency for female sterilisation 2016 · Cochrane Headline outcomes only
OR 0.21
2 studies · 3537 participants
Moderate