Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,935 questions · 1,986 findings · 260 reviews · Headline outcomes only

No studies found 503 · 25.3%GRADE not reported 76 · 3.8%Very low 593 · 29.9%Low 509 · 25.6%Moderate 241 · 12.1%High 64 · 3.2%

Psychological therapies vs antidepressants alone or antidepressants and benzodiazepines

Short‐term remission · adults with panic disorder

All psychological therapies showed no clear difference in short‐term remission compared with antidepressants alone or antidepressants and benzodiazepines (low certainty).

1 finding from 1 review

Psychological therapies vs antidepressants alone or antidepressants and benzodiazepines

Short‐term response · adults with panic disorder

All psychological therapies showed no clear difference in short‐term response compared with antidepressants alone or antidepressants and benzodiazepines (low certainty).

1 finding from 1 review

Psychological therapies vs antidepressants alone or antidepressants and benzodiazepines

Leaving the study early · adults with panic disorder

It is very uncertain whether all psychological therapies changes dropouts for any reason compared with antidepressants alone or antidepressants and benzodiazepines (very low certainty).

1 finding from 1 review

Psychological therapies vs antidepressants alone or antidepressants and benzodiazepines

Short‐term improvement Scale used (range; lower is better): panic frequency Clinical Global Impression (1 to 7) Agoraphobic Cognitive Questionnaire (1 to 70) Fear Questionnaire Agoraphobia Subscale (0 to 14) Brief Scale for Anxiety (0 to 60) STAI ... · adults with panic disorder
1 finding from 1 review

Heparin vs no treatment

Mortality attributable to hepatic veno‐occlusive disease ( · People undergoing autologous or HLA identical allogeneic bone marrow transplant with a variety of malignant diseases or aplastic anaemia

Summary of findings: Heparin showed no clear difference in mortality attributable to hepatic veno‐occlusive disease ( compared with no treatment (low certainty).

1 finding from 1 review

Heparin vs no treatment

Frequency of adverse events ( · People undergoing autologous or HLA identical allogeneic bone marrow transplant with a variety of malignant diseases or aplastic anaemia

It is very uncertain whether summary of findings: Heparin changes frequency of adverse events ( compared with no treatment (very low certainty).

1 finding from 1 review

Summary of findings: Antithrombin III plus heparin vs heparin

Incidence of hepatic veno‐occlusive disease ( · Patients undergoing stem cell transplant with malignant and non‐malignant diseases

It is very uncertain whether summary of findings: Antithrombin III plus heparin changes incidence of hepatic veno‐occlusive disease ( compared with heparin alone (very low certainty).

1 finding from 1 review

Summary of findings: Antithrombin III plus heparin vs heparin

Mortality attributable to hepatic veno‐occlusive disease ( · Patients undergoing stem cell transplant with malignant and non‐malignant diseases

It is very uncertain whether summary of findings: Antithrombin III plus heparin changes mortality attributable to hepatic veno‐occlusive disease ( compared with heparin alone (very low certainty).

1 finding from 1 review

Summary of findings: Antithrombin III plus heparin vs heparin

Frequency of adverse events ( · Patients undergoing stem cell transplant with malignant and non‐malignant diseases

It is very uncertain whether summary of findings: Antithrombin III plus heparin changes frequency of adverse events ( compared with heparin alone (very low certainty).

1 finding from 1 review

Heparin vs no treatment

Incidence of hepatic veno‐occlusive disease ( · People undergoing autologous or HLA identical allogeneic bone marrow transplant with a variety of malignant diseases or aplastic anaemia

It is very uncertain whether summary of findings: Heparin changes incidence of hepatic veno‐occlusive disease ( compared with no treatment (very low certainty).

1 finding from 1 review

Heparin vs no treatment

Overall survival ( · People undergoing autologous or HLA identical allogeneic bone marrow transplant with a variety of malignant diseases or aplastic anaemia

It is very uncertain whether summary of findings: Heparin changes overall survival ( compared with no treatment (very low certainty).

1 finding from 1 review

Heparin vs no treatment

All‐cause mortality at 100 days post‐transplant · People undergoing autologous or HLA identical allogeneic bone marrow transplant with a variety of malignant diseases or aplastic anaemia

Summary of findings: Heparin showed no clear difference in all‐cause mortality at 100 days post‐transplant ( compared with no treatment (low certainty).

1 finding from 1 review