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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

2,434 questions in 139 reviews · Kidney and Transplant

current versions
No studies 504 · 20.7%Ungraded 40 · 1.6%Very low 611 · 25.1%Low 790 · 32.5%Moderate 414 · 17%High 75 · 3.1%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Peritoneoscopic vs open surgical PD catheter insertion
Catheter tip migration (mechanical failure) · improving catheter function and clinical outcomes in PD patients
Catheter insertion techniques for improving catheter function and clinical outcomes in peritoneal dialysis… (2023) · Cochrane
RR 0.36 [0.02, 8.07]1 study · 29 participantsVery low
Laparoscopic vs open surgical PD catheter insertion
Technique failure · patients requiring PD catheter placement
Catheter insertion techniques for improving catheter function and clinical outcomes in peritoneal dialysis… (2023) · Cochrane
no estimate extractedNRNo studies
Laparoscopic vs open surgical PD catheter insertion
Postoperative death (relating to PD catheter insertion) · patients requiring PD catheter placement
Catheter insertion techniques for improving catheter function and clinical outcomes in peritoneal dialysis… (2023) · Cochrane
RR 0.32 [0.01, 7.63]2 studies · 167 participantsVery low
Laparoscopic vs open surgical PD catheter insertion
Peritonitis Time frame: within 4 weeks of PD catheter insertion · patients requiring PD catheter placement
Catheter insertion techniques for improving catheter function and clinical outcomes in peritoneal dialysis… (2023) · Cochrane
RR 0.97 [0.63, 1.48]4 studies · 288 participantsLow
Laparoscopic vs open surgical PD catheter insertion
Dialysate leakage (excluding Tsimoyiannis 2000) · patients requiring PD catheter placement
Catheter insertion techniques for improving catheter function and clinical outcomes in peritoneal dialysis… (2023) · Cochrane
RR 1.4 [0.49, 4.02]4 studies · 330 participantsLow
Laparoscopic vs open surgical PD catheter insertion
Catheter tip migration (mechanical failure) · patients requiring PD catheter placement
Catheter insertion techniques for improving catheter function and clinical outcomes in peritoneal dialysis… (2023) · Cochrane
RR 0.43 [0.2, 0.92]4 studies · 333 participantsLow
Medical vs open surgical PD catheter insertion
Early PD catheter function (within 4 weeks of PD catheter insertion) · improving catheter function and clinical outcomes in PD patients
Catheter insertion techniques for improving catheter function and clinical outcomes in peritoneal dialysis… (2023) · Cochrane
RR 0.73 [0.29, 1.83]3 studies · 212 participantsLow
Medical vs open surgical PD catheter insertion
Late PD catheter failure (> 4 weeks following PD catheter insertion) · improving catheter function and clinical outcomes in PD patients
Catheter insertion techniques for improving catheter function and clinical outcomes in peritoneal dialysis… (2023) · Cochrane
RR 0.59 [0.38, 0.92]1 study · 116 participantsVery low
Exercise vs control
Fatigue (IFS, MFI, PIPER, or HD‐related fatigue scale) median · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extracted4 studies · 217 participantsLow
Aromatherapy vs placebo or standard care
Tiredness · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extractedNRNo studies
Aromatherapy vs placebo or standard care
Exhaustion · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extractedNRNo studies
Aromatherapy vs placebo or standard care
Asthenia · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extractedNRNo studies
Massage vs no intervention
Fatigue (PFS, FSS, VAS) median · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extracted7 studies · 657 participantsLow
Massage vs no intervention
Weakness · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extractedNRNo studies
Massage vs no intervention
Energy (VAS) median · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extracted2 studies · 152 participantsLow
Massage vs no intervention
Tiredness · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extractedNRNo studies
Massage vs no intervention
Exhaustion · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extractedNRNo studies
Massage vs no intervention
Asthenia · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extractedNRNo studies
Acupressure vs placebo or control
Fatigue [PFS, revised PFS, FI] median · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extracted6 studies · 459 participantsLow
Exercise vs control
Weakness · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extractedNRNo studies
Acupressure vs placebo or control
Weakness · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extractedNRNo studies
Acupressure vs placebo or control
Energy · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extractedNRNo studies
Acupressure vs placebo or control
Tiredness · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extractedNRNo studies
Acupressure vs placebo or control
Exhaustion · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extractedNRNo studies
Acupressure vs placebo or control
Asthenia · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extractedNRNo studies
Exercise vs control
Energy · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extractedNRNo studies
Exercise vs control
Tiredness · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extractedNRNo studies
Exercise vs control
Exhaustion · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extractedNRNo studies
Exercise vs control
Asthenia · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extractedNRNo studies
Aromatherapy vs placebo or standard care
Fatigue (PIPER, BFI, FSS, RFS) median · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extracted7 studies · 542 participantsLow
Aromatherapy vs placebo or standard care
Weakness · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extractedNRNo studies
Aromatherapy vs placebo or standard care
Energy · people receiving dialysis
Interventions for fatigue in people with kidney failure requiring dialysis (2023) · Cochrane
no estimate extractedNRNo studies
Synbiotic vs another synbiotic
eGFR · people with CKD
Synbiotics, prebiotics and probiotics for people with chronic kidney disease (2023) · Cochrane
no estimate extractedNRNo studies
Synbiotic vs prebiotic
Indoxyl sulfate (ng/mL) · people with CKD
Synbiotics, prebiotics and probiotics for people with chronic kidney disease (2023) · Cochrane
no estimate extracted1 study · 42 participantsVery low
Synbiotic vs prebiotic
Change in any GI upset (borborygmi) · people with CKD
Synbiotics, prebiotics and probiotics for people with chronic kidney disease (2023) · Cochrane
RR 15.26 [0.99, 236.23]1 study · 34 participantsVery low
Synbiotic vs prebiotic
Change in any GI upset (GSRS total index) · people with CKD
Synbiotics, prebiotics and probiotics for people with chronic kidney disease (2023) · Cochrane
no estimate extracted1 study · 56 participantsVery low
Synbiotic vs prebiotic
Microbiota composition · people with CKD
Synbiotics, prebiotics and probiotics for people with chronic kidney disease (2023) · Cochrane
no estimate extractedNRNo studies
Synbiotic vs prebiotic
Graft function · people with CKD
Synbiotics, prebiotics and probiotics for people with chronic kidney disease (2023) · Cochrane
no estimate extractedNRNo studies
Synbiotic vs prebiotic
Graft infection · people with CKD
Synbiotics, prebiotics and probiotics for people with chronic kidney disease (2023) · Cochrane
no estimate extractedNRNo studies
Prebiotic vs another prebiotic
eGFR (mL/min) · people with CKD
Synbiotics, prebiotics and probiotics for people with chronic kidney disease (2023) · Cochrane
no estimate extracted1 study · 50 participantsVery low
Prebiotic vs another prebiotic
Albuminuria or proteinuria · people with CKD
Synbiotics, prebiotics and probiotics for people with chronic kidney disease (2023) · Cochrane
no estimate extractedNRNo studies
Prebiotic vs another prebiotic
Indoxyl sulfate (μg/mL) · people with CKD
Synbiotics, prebiotics and probiotics for people with chronic kidney disease (2023) · Cochrane
no estimate extracted2 studies · 64 participantsVery low
Prebiotic vs another prebiotic
Change in any GI upset or intolerance · people with CKD
Synbiotics, prebiotics and probiotics for people with chronic kidney disease (2023) · Cochrane
no estimate extracted1 study · 24 participantsVery low
Synbiotic vs another synbiotic
Albuminuria or proteinuria · people with CKD
Synbiotics, prebiotics and probiotics for people with chronic kidney disease (2023) · Cochrane
no estimate extractedNRNo studies
Prebiotic vs another prebiotic
Burping · people with CKD
Synbiotics, prebiotics and probiotics for people with chronic kidney disease (2023) · Cochrane
no estimate extracted1 study · 24 participantsVery low
Prebiotic vs another prebiotic
Cramping · people with CKD
Synbiotics, prebiotics and probiotics for people with chronic kidney disease (2023) · Cochrane
no estimate extracted1 study · 24 participantsVery low
Prebiotic vs another prebiotic
Distension · people with CKD
Synbiotics, prebiotics and probiotics for people with chronic kidney disease (2023) · Cochrane
no estimate extracted1 study · 24 participantsVery low
Prebiotic vs another prebiotic
Flatulence · people with CKD
Synbiotics, prebiotics and probiotics for people with chronic kidney disease (2023) · Cochrane
no estimate extracted1 study · 24 participantsVery low
Prebiotic vs another prebiotic
Nausea · people with CKD
Synbiotics, prebiotics and probiotics for people with chronic kidney disease (2023) · Cochrane
no estimate extracted1 study · 24 participantsVery low
Prebiotic vs another prebiotic
Reflux · people with CKD
Synbiotics, prebiotics and probiotics for people with chronic kidney disease (2023) · Cochrane
no estimate extracted1 study · 24 participantsVery low