Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

191 questions · 200 findings · 15 reviews

No studies found 94 · 47%GRADE not reported 1 · 0.5%Very low 70 · 35%Low 27 · 13.5%Moderate 7 · 3.5%High 1 · 0.5%

Iodine vs topical antibiotics

Infection · people with burns

The review found no eligible studies for this question.

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Iodine vs topical antibiotics

Adverse events · people with burns

It is very uncertain whether iodine changes adverse events compared with topical antibiotics (very low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    RR 0.86 [0.35, 2.1]
    1 study · 40 participants
    Very low

Silver‐based antiseptics vs topical antibiotics

Wound healing · people with burns

Silver‐based antiseptics showed no clear difference in wound healing (mean time to healing) compared with topical antibiotics (low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    no estimate extracted
    10 studies · 1085 participants
    Low

Silver‐based antiseptics vs topical antibiotics

Number of wounds healed · people with burns

Silver‐based antiseptics showed no clear difference in wound healing (number of healing events) compared with topical antibiotics (low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    RR 1.17 [1, 1.37]
    5 studies · 408 participants
    Low

Honey vs topical antibiotics

Time to complete healing · people with burns

Honey probably leads to higher wound healing: time to complete healing (time‐to‐event data): honey… compared with topical antibiotics (moderate certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    HR 2.45 [1.71, 3.52]
    5 studies · 580 participants
    Moderate

Honey vs topical antibiotics

Wound healing · people with burns

It is very uncertain whether honey changes wound healing (mean time to healing): honey versus SSD compared with topical antibiotics (very low certainty).

2 findings from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    no estimate extracted
    6 studies · 712 participants
    Very low
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    RR 2.18 [1.15, 4.13]
    4 studies · 318 participants
    Low

Honey vs topical antibiotics

Incident infection: honey versus SSD or mafenide acetate · people with burns

It is very uncertain whether honey changes incident infection: honey versus SSD or mafenide acetate compared with topical antibiotics (very low certainty).

1 finding from 1 review
  • Antiseptics for burns 2017 · Cochrane Headline outcomes only
    RR 0.16 [0.08, 0.34]
    4 studies · 480 participants
    Very low

Oral vs topical antibiotics

Active trachoma · people (any age) with active trachoma

Oral showed no clear difference in active trachoma Clinical assessment: active trachoma defined as TF,… compared with topical antibiotic (low certainty).

1 finding from 1 review

Oral vs topical antibiotics

Antibiotic resistance · people (any age) with active trachoma

The review found no eligible studies for this question.

1 finding from 1 review
  • Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Intervention not reported

Health‐related quality of life · CSOM, recurrence of CSOM or suppuration following mastoidectomy or tympanoplasty

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Ear pain (otalgia) or discomfort or local irritation · CSOM, recurrence of CSOM or suppuration following mastoidectomy or tympanoplasty

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Hearing · CSOM, recurrence of CSOM or suppuration following mastoidectomy or tympanoplasty

The review found no eligible studies for this question.

1 finding from 1 review