Findings

What do systematic reviews say?

272 questions · 286 findings · 20 reviews · Schizophrenia

Sort:Best matchNewest Highest certainty Download CSV

No studies found 49 · 17.1%GRADE not reported 30 · 10.5%Very low 88 · 30.8%Low 42 · 14.7%Moderate 73 · 25.5%High 4 · 1.4%

Zuclopenthixol dihydrochloride vs RISPERIDONE

Length of hospital stay · schizophrenia

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Zuclopenthixol dihydrochloride vs RISPERIDONE

Mental state · schizophrenia

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 25 participants
Very low

Zuclopenthixol dihydrochloride vs RISPERIDONE

Leaving the study early · schizophrenia

It is very uncertain whether zuclopenthixol dihydrochloride changes leaving the study early (any reason, short and medium term) compared with risperidone (very low certainty).

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
RR 1.3 [0.84, 2.02]
3 studies · 154 participants
Very low

Zuclopenthixol dihydrochloride vs RISPERIDONE

General functioning: Average endpoint general functioning score (clinically improved) (no data) · schizophrenia

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

HALOPERIDOL vs COMBINATIONS: e. HALOPERIDOL + RISPERIDONE

Tranquillisation or asleep ‐ not reported · psychosis‐induced aggression or agitation

The review found no eligible studies for this question.

1 finding from 1 review

Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

HALOPERIDOL vs COMBINATIONS: e. HALOPERIDOL + RISPERIDONE

Repeated need for tranquillisation ‐ not reported · psychosis‐induced aggression or agitation

The review found no eligible studies for this question.

1 finding from 1 review

Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

HALOPERIDOL vs COMBINATIONS: e. HALOPERIDOL + RISPERIDONE

Specific behaviour ‐ agitation · psychosis‐induced aggression or agitation

1 finding from 1 review

Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 100 participants
Low

HALOPERIDOL vs COMBINATIONS: e. HALOPERIDOL + RISPERIDONE

Global outcome · psychosis‐induced aggression or agitation

HALOPERIDOL showed no clear difference in global outcome compared with COMBINATIONS: e. HALOPERIDOL + RISPERIDONE (low certainty).

1 finding from 1 review

Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) 2017 · Cochrane Headline outcomes only
RR 0.38 [0.11, 1.33]
1 study · 100 participants
Low

HALOPERIDOL vs COMBINATIONS: e. HALOPERIDOL + RISPERIDONE

Specific adverse events · psychosis‐induced aggression or agitation

HALOPERIDOL showed no clear difference in adverse effects: specific compared with COMBINATIONS: e. HALOPERIDOL + RISPERIDONE (low certainty).

1 finding from 1 review

Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) 2017 · Cochrane Headline outcomes only
RR 0.88 [0.48, 1.6]
1 study · 100 participants
Low

HALOPERIDOL vs COMBINATIONS: e. HALOPERIDOL + RISPERIDONE

Economic outcome ‐ not reported · psychosis‐induced aggression or agitation

The review found no eligible studies for this question.

1 finding from 1 review

Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

HALOPERIDOL vs COMBINATIONS: h. RISPERIDONE + CLONAZEPAM

Tranquillisation or asleep · psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes tranquillisation or asleep compared with COMBINATIONS: h. RISPERIDONE + CLONAZEPAM (very low certainty).

1 finding from 1 review

Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) 2017 · Cochrane Headline outcomes only
RR 0.82 [0.66, 1.03]
1 study · 205 participants
Very low

HALOPERIDOL vs COMBINATIONS: h. RISPERIDONE + CLONAZEPAM

Repeated need for tranquillisation ‐ not reported · psychosis‐induced aggression or agitation

The review found no eligible studies for this question.

1 finding from 1 review

Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

HALOPERIDOL vs COMBINATIONS: h. RISPERIDONE + CLONAZEPAM

Specific behaviour ‐ agitation · psychosis‐induced aggression or agitation

1 finding from 1 review

Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 108 participants
Very low

HALOPERIDOL vs COMBINATIONS: h. RISPERIDONE + CLONAZEPAM

Global outcome · psychosis‐induced aggression or agitation

HALOPERIDOL showed no clear difference in global outcome compared with COMBINATIONS: h. RISPERIDONE + CLONAZEPAM (low certainty).

1 finding from 1 review

Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) 2017 · Cochrane Headline outcomes only
RR 0.6 [0.15, 2.38]
1 study · 100 participants
Low

HALOPERIDOL vs COMBINATIONS: h. RISPERIDONE + CLONAZEPAM

Adverse effects · psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes adverse effects compared with COMBINATIONS: h. RISPERIDONE + CLONAZEPAM (very low certainty).

1 finding from 1 review

Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) 2017 · Cochrane Headline outcomes only
RR 1.63 [1.12, 2.38]
1 study · 205 participants
Very low

HALOPERIDOL vs COMBINATIONS: h. RISPERIDONE + CLONAZEPAM

Economic outcome ‐ not reported · psychosis‐induced aggression or agitation

The review found no eligible studies for this question.

1 finding from 1 review

Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

HALOPERIDOL vs RISPERIDONE

Tranquilisation or asleep Not asleep · patients with psychosis‐induced aggression or agitation

HALOPERIDOL probably leads to lower tranquillisation or asleep ‐ not asleep compared with OTHER ANTIPSYCHOTIC: h. RISPERIDONE (moderate certainty).

1 finding from 1 review

Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) 2017 · Cochrane Headline outcomes only
RR 0.84 [0.74, 0.95]
1 study · 162 participants
Moderate

HALOPERIDOL vs RISPERIDONE

Repeated need for rapid tranquillisation ‐ needing additional benzodiazepine · patients with psychosis‐induced aggression or agitation

HALOPERIDOL showed no clear difference in repeated need for rapid tranquillisation ‐ needing additional… compared with OTHER ANTIPSYCHOTIC: h. RISPERIDONE (low certainty).

1 finding from 1 review

Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) 2017 · Cochrane Headline outcomes only
RR 0.98 [0.65, 1.47]
2 studies · 286 participants
Low

HALOPERIDOL vs RISPERIDONE

Specific behaviours ‐ agitation >50% reduction in PANSS‐EC score · patients with psychosis‐induced aggression or agitation

HALOPERIDOL showed no clear difference in specific behaviours ‐ agitation >50% reduction in PANSS‐EC score compared with OTHER ANTIPSYCHOTIC: h. RISPERIDONE (low certainty).

1 finding from 1 review

Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) 2017 · Cochrane Headline outcomes only
RR 1.15 [0.6, 2.22]
1 study · 124 participants
Low

HALOPERIDOL vs RISPERIDONE

Global outcome ‐ rated as severe ‐ CGI‐S · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes global outcome ‐ rated as severe ‐ CGI‐S compared with OTHER ANTIPSYCHOTIC: h. RISPERIDONE (very low certainty).

1 finding from 1 review

Haloperidol for psychosis‐induced aggression or agitation (rapid tranquillisation) 2017 · Cochrane Headline outcomes only
RR 0.89 [0.51, 1.58]
1 study · 162 participants
Very low