Findings

What do systematic reviews say?

162 questions · 167 findings · 24 reviews · Musculoskeletal

No studies found 65 · 38.9%GRADE not reported 6 · 3.6%Very low 24 · 14.4%Low 55 · 32.9%Moderate 16 · 9.6%High 1 · 0.6%

Acute gout attacks · people with chronic gout

Benzbromarone showed no clear difference in acute gout attacks compared with probenecid (low certainty).

1 finding from 1 review

Uricosuric medications for chronic gout 2014 · Cochrane Headline outcomes only
RR 0.73 [0.09, 5.83]
2 studies · 129 participants
Low

Serum urate normalisation ≤ 5 mg/dL (≤ 0.3 mmol/L) · people with chronic gout

Benzbromarone probably leads to higher serum urate normalisation ≤ 5 mg/dL (≤ 0.3 mmol/L) compared with probenecid (moderate certainty).

1 finding from 1 review

Uricosuric medications for chronic gout 2014 · Cochrane Headline outcomes only
RR 1.43 [1.02, 2]
1 study · 62 participants
Moderate