What do systematic reviews say?

Starting administration of the progestogen earlier vs starting administration of the progestogen later

• Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 282 participants
  Very low

GnRH agonists vs control

GnRH agonists showed no clear difference in clinical pregnancy rate compared with control (low certainty).

• Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
  OR 1.08 [0.82, 1.43]
  8 studies · 1289 participants
  Low

GnRH agonists vs control

The review found no eligible studies for this question.

• Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

GnRH agonists vs placebo

It is very uncertain whether among different GnRH agonists changes clinical pregnancy rate compared with placebo (very low certainty).

• Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
  OR 1.93 [0.62, 5.98]
  1 study · 50 participants
  Very low

GnRH agonists vs placebo

The review found no eligible studies for this question.

• Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Stimulated cycle vs programmed

The review found no eligible studies for this question.

• Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

GnRH agonists vs GnRH antagonists

GnRH agonists probably leads to lower clinical pregnancy rate compared with gnRH antagonists (moderate certainty).

• Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
  OR 0.62 [0.42, 0.9]
  1 study · 473 participants
  Moderate

GnRH agonists vs GnRH antagonists

GnRH agonists showed no clear difference in multiple pregnancy rate compared with gnRH antagonists (low certainty).

• Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
  OR 0.69 [0.45, 1.07]
  1 study · 473 participants
  Low

Aspirin vs control

It is very uncertain whether aspirin changes clinical pregnancy rate compared with control (very low certainty).

• Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
  OR 3.33 [1, 11.14]
  1 study · 60 participants
  Very low

Aspirin vs control

The review found no eligible studies for this question.

• Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Steroids vs control

It is very uncertain whether steroids changes clinical pregnancy rate compared with control (very low certainty).

• Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
  OR 0.9 [0.4, 2.03]
  2 studies · 160 participants
  Very low

Steroids vs control

The review found no eligible studies for this question.

• Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Natural cycle vs programmed cycle

It is very uncertain whether natural cycle changes clinical pregnancy rate compared with programmed cycle (very low certainty).

• Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
  OR 0.79 [0.62, 1.01]
  5 studies · 1249 participants
  Very low

Gradient technique vs wash and centrifugation

It is very uncertain whether gradient technique changes clinical pregnancy rate per couple compared with wash and centrifugation (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 1.78 [0.58, 5.46]
  2 studies · 94 participants
  Very low

Gradient technique vs wash and centrifugation

The review found no eligible studies for this question.

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Gradient technique vs wash and centrifugation

It is very uncertain whether gradient technique changes multiple pregnancy rate per couple compared with wash and centrifugation (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 0.33 [0.01, 8.83]
  1 study · 31 participants
  Very low

Swim‐up technique vs gradient technique

It is very uncertain whether swim‐up technique changes clinical pregnancy rate per couple compared with gradient technique (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 0.83 [0.51, 1.35]
  4 studies · 370 participants
  Very low

Swim‐up technique vs gradient technique

It is very uncertain whether swim‐up technique changes ongoing pregnancy rate per couple compared with gradient technique (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 0.39 [0.19, 0.82]
  1 study · 223 participants
  Very low

Swim‐up technique vs gradient technique

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 25 participants
  Very low

Swim‐up technique vs wash and centrifugation

It is very uncertain whether swim‐up technique changes clinical pregnancy rate per couple compared with wash and centrifugation (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 0.41 [0.15, 1.13]
  2 studies · 78 participants
  Very low