Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

241 questions · 264 findings · 24 reviews

No studies found 84 · 31.8%GRADE not reported 5 · 1.9%Very low 83 · 31.4%Low 64 · 24.2%Moderate 21 · 8%High 7 · 2.7%

Morphine vs diamorphine

Neurodevelopmental outcomes · neonates with mechanical ventilation

The review found no eligible studies for this question.

3 findings from 1 review

Fentanyl vs sufentanil

Neurodevelopmental outcomes · neonates with mechanical ventilation

The review found no eligible studies for this question.

3 findings from 1 review

Fentanyl vs remifentanil

Neurodevelopmental outcomes · neonates with mechanical ventilation

The review found no eligible studies for this question.

3 findings from 1 review

IM pethidine vs placebo

Maternal satisfaction with analgesia measured during labour (number of women satisfied or very satisfied after 30 minutes) · women in labour

It is very uncertain whether IM pethidine changes maternal satisfaction with analgesia measured during labour (number… compared with placebo (very low certainty).

1 finding from 1 review

Intervention not reported

Maternal satisfaction with analgesia (Analgesic effect described as satisfactory (not clear when measured))
1 finding from 1 review

Intervention not reported

Maternal pain score or pain measured in labour (Pain intensity 4 or 5 on 5‐point scale (1 hour))
1 finding from 1 review