Intervention not reported
All‐cause graft loss (including CNI) · kidney transplant recipients
The intervention showed no clear difference in all‐cause graft loss (including CNI) (low certainty).
1 finding from 1 review
Intervention not reported
Delayed graft function · kidney transplant recipients
The intervention showed no clear difference in delayed graft function (low certainty).
1 finding from 1 review
Intervention not reported
Acute rejection (including CNI) · kidney transplant recipients
The intervention probably leads to lower acute rejection (including CNI) (moderate certainty).
1 finding from 1 review
Intervention not reported
Infection: CMV infection · kidney transplant recipients
The intervention probably leads to higher infection: CMV infection (moderate certainty).
1 finding from 1 review
Intervention not reported
Malignancy · kidney transplant recipients
The intervention showed no clear difference in malignancy (low certainty).
1 finding from 1 review
Intervention not reported
Death (ESW both arms) · kidney transplant recipients
The intervention showed no clear difference in death (ESW both arms) (low certainty).
1 finding from 1 review
Intervention not reported
All‐cause graft loss (ESW both arms) · kidney transplant recipients
The intervention showed no clear difference in all‐cause graft loss (ESW both arms) (low certainty).
1 finding from 1 review
Intervention not reported
Acute rejection (ESW both arms) · kidney transplant recipients
The intervention probably leads to lower acute rejection (ESW both arms) (moderate certainty).
1 finding from 1 review
Intervention not reported
OS (at 3 years) · newly diagnosed or relapsed patients with CLL
The intervention leads to lower OS (at 3 years) (high certainty).
1 finding from 1 review
Intervention not reported
TRM · newly diagnosed or relapsed patients with CLL
The intervention showed no clear difference in TRM (low certainty).
1 finding from 1 review
Intervention not reported
PFS (at 3 years) · newly diagnosed or relapsed patients with CLL
The intervention probably leads to lower PFS (at 3 years) (moderate certainty).
1 finding from 1 review
Intervention not reported
TRM · newly diagnosed or relapsed patients with CLL
The intervention showed no clear difference in TRM (moderate certainty).
1 finding from 1 review
Intervention not reported
SAEs ‐ overall analysis · newly diagnosed or relapsed patients with CLL
The intervention showed no clear difference in SAEs ‐ overall analysis (low certainty).
1 finding from 1 review
Intervention not reported
Grade 3/4 AEs ‐ overall analysis · newly diagnosed or relapsed patients with CLL
The intervention probably leads to higher grade 3/4 AEs ‐ overall analysis (moderate certainty).
1 finding from 1 review
Intervention not reported
OS not reported · newly diagnosed or relapsed patients with CLL
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
PFS not reported · newly diagnosed or relapsed patients with CLL
1 finding from 1 review
no estimate extracted
0 participants
GRADE not reported
Intervention not reported
Time to next treatment · newly diagnosed or relapsed patients with CLL
1 finding from 1 review
no estimate extracted
0 participants
GRADE not reported
Intervention not reported
CRR · newly diagnosed or relapsed patients with CLL
The intervention showed no clear difference in CRR (moderate certainty).
1 finding from 1 review