Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,156 questions · 1,179 findings · 198 reviews · Headline outcomes only

No studies found 250 · 21.2%GRADE not reported 43 · 3.6%Very low 236 · 20%Low 395 · 33.5%Moderate 208 · 17.6%High 47 · 4%

Sildenafil vs placebo

Global Efficacy Questionnaire (questions 1 & 2) (Questions assessing improvement attributed to medication compared to having no treatment at all) · people with antidepressant‐induced sexual dysfunction

Sildenafil probably leads to higher global Efficacy Questionnaire (questions 1 & 2) (Questions assessing… compared with placebo (moderate certainty).

1 finding from 1 review