Findings

What do systematic reviews say?

369 questions · 377 findings · 28 reviews · Schizophrenia

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No studies found 101 · 26.8%GRADE not reported 54 · 14.3%Very low 133 · 35.3%Low 63 · 16.7%Moderate 26 · 6.9%High 0 · 0%

GROUP PSYCHOSOCIAL THERAPY (GPT) + TAU vs TAU

Global state: Average endpoint score CGAS (high score = good) · Adolescents with psychosis

1 finding from 1 review

Psychological interventions for psychosis in adolescents 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 56 participants
Very low

GROUP PSYCHOSOCIAL THERAPY (GPT) + TAU vs TAU

Mental state · Adolescents with psychosis

1 finding from 1 review

Psychological interventions for psychosis in adolescents 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 56 participants
Very low

CANNABIS REDUCTION: ADJUNCT PSYCHOLOGICAL THERAPY vs treatment

General mental state: Positive psychiatric symptom score PANSS5. Scale from: 7 to 49. · patients with SCHIZOPHRENIA AND CANNABIS USE

1 finding from 1 review

Cannabis and schizophrenia 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 62 participants
Moderate

CANNABIS REDUCTION: ADJUNCT PSYCHOLOGICAL THERAPY vs treatment

Global state: relapse ‐ medium term ‐ not measured · patients with SCHIZOPHRENIA AND CANNABIS USE

The review found no eligible studies for this question.

1 finding from 1 review

Cannabis and schizophrenia 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

CANNABIS REDUCTION: ADJUNCT PSYCHOLOGICAL THERAPY vs treatment

Average change in quality of life/satisfaction · patients with SCHIZOPHRENIA AND CANNABIS USE

1 finding from 1 review

Cannabis and schizophrenia 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 49 participants
Moderate

CANNABIS REDUCTION: ADJUNCT PSYCHOLOGICAL THERAPY vs treatment

Adverse effects: no clinically important adverse effects ‐ medium term ‐ not measured · patients with SCHIZOPHRENIA AND CANNABIS USE

The review found no eligible studies for this question.

1 finding from 1 review

Cannabis and schizophrenia 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

CANNABIS REDUCTION: ADJUNCT PSYCHOLOGICAL THERAPY vs treatment

Leaving the study early ‐ medium term ‐ not reported · patients with SCHIZOPHRENIA AND CANNABIS USE

The review found no eligible studies for this question.

1 finding from 1 review

Cannabis and schizophrenia 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

CANNABIS REDUCTION: ADJUNCT PSYCHOLOGICAL THERAPY vs treatment

Satisfaction with treatment ‐ medium term ‐ not measured · patients with SCHIZOPHRENIA AND CANNABIS USE

The review found no eligible studies for this question.

1 finding from 1 review

Cannabis and schizophrenia 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Lost to treatment · people with both severe mental illness and substance misuse

Cognitive behavioural therapy + motivational interviewing showed no clear difference in leaving the study early: Lost to treatment compared with standard care (low certainty).

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
RR 0.99 [0.62, 1.59]
1 study · 327 participants
Low

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Adverse event: Death · people with both severe mental illness and substance misuse

Cognitive behavioural therapy + motivational interviewing showed no clear difference in adverse event: Death compared with standard care (low certainty).

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
RR 0.6 [0.2, 1.76]
4 studies · 603 participants
Low

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Alcohol use Estimated daily consumption in previous month · people with both severe mental illness and substance misuse

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 46 participants
GRADE not reported

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Drug (non‐alcohol) use Polydrug consumption levels measured by Opiate Treatment Index (OT) · people with both severe mental illness and substance misuse

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 119 participants
Low

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Relapse · people with both severe mental illness and substance misuse

It is very uncertain whether cognitive behavioural therapy + motivational interviewing changes relapse:* Relapse at 3 months after 9 months of treatment compared with standard care (very low certainty).

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
RR 0.5 [0.24, 1.04]
1 study · 36 participants
Very low

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Global state: average score(GAF scale of 1 ‐ 100) · people with both severe mental illness and substance misuse

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 445 participants
Very low

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Quality of life / life satisfaction: Brief Quality of Life Scale · people with both severe mental illness and substance misuse

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 110 participants
Low

Cognitive behavioural therapy + intensive case management vs usual care

Lost to treatment · people with both severe mental illness and substance misuse

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Very low

Cognitive behavioural therapy + intensive case management vs usual care

Adverse event: Death · people with both severe mental illness and substance misuse

The review found no eligible studies for this question.

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Cognitive behavioural therapy + intensive case management vs usual care

Alcohol use ‐ not measured · people with both severe mental illness and substance misuse

The review found no eligible studies for this question.

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Cognitive behavioural therapy + intensive case management vs usual care

Drug (non‐alcohol) use ‐ not measured · people with both severe mental illness and substance misuse

The review found no eligible studies for this question.

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Cognitive behavioural therapy + intensive case management vs usual care

Mental state ‐ not measured · people with both severe mental illness and substance misuse

The review found no eligible studies for this question.

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found