Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

329 questions · 344 findings · 34 reviews · Gut

No studies found 31 · 9%GRADE not reported 6 · 1.7%Very low 101 · 29.4%Low 82 · 23.8%Moderate 86 · 25%High 38 · 11%

Intervention not reported

Chemobased OS ‐ 5‐FU based chemotherapy OS · patients with resectable gastric cancer

The intervention probably leads to lower chemobased OS ‐ 5‐FU based chemotherapy OS (moderate certainty).

1 finding from 1 review

Intervention not reported

Chemobased OS ‐ Platinum‐based chemotherapy OS · patients with resectable gastric cancer

The intervention showed no clear difference in chemobased OS ‐ Platinum‐based chemotherapy OS (moderate certainty).

1 finding from 1 review

Intervention not reported

Chemobased DFS ‐ 5‐FU based chemotherapy DFS · patients with resectable gastric cancer

The intervention probably leads to lower chemobased DFS ‐ 5‐FU based chemotherapy DFS (moderate certainty).

1 finding from 1 review

Intervention not reported

Chemobased DFS ‐ Platinum‐based chemotherapy DFS · patients with resectable gastric cancer

The intervention showed no clear difference in chemobased DFS ‐ Platinum‐based chemotherapy DFS (moderate certainty).

1 finding from 1 review

H. pylori eradication therapy vs control

Incidence of gastric cancer ‐ modified ITT analysis Histological examination · healthy asymptomatic H. pylori‐infected individuals

H. pylori eradication therapy probably leads to lower incidence of gastric cancer ‐ modified ITT analysisHistological… compared with control (moderate certainty).

1 finding from 1 review

H. pylori eradication therapy vs control

Incidence of oesophageal squamous cell carcinoma ‐ modified ITT analysis · healthy asymptomatic H. pylori‐infected individuals

H. pylori eradication therapy showed no clear difference in incidence of oesophageal squamous cell carcinoma ‐ modified ITT… compared with control (moderate certainty).

1 finding from 1 review