Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

186 questions · 206 findings · 16 reviews · Developmental, Psychosocial and Learning Problems

No studies found 46 · 22.3%GRADE not reported 6 · 2.9%Very low 48 · 23.3%Low 84 · 40.8%Moderate 21 · 10.2%High 1 · 0.5%

Dialectical behavioural therapy or mentalisation‐based therapy vs usual care

Suicide‐related outcomes Timing of outcome assessment: end of treatment (6 to 12 weeks treatment duration) · patients with borderline personality disorder

Dialectical behavioural therapy or mentalisation‐based therapy may leads to lower suicide‐related outcomes Measured by: clinicians Timing of outcome… compared with treatment‐as‐usual (low certainty).

1 finding from 1 review

Systems training for emotional predictability and problem solving for borderline personality disorder + individual therapy (STEPPS+IT) vs treatment

Impulsivity · patients with borderline personality disorder

Systems training for emotional predictability and problem solving… showed no clear difference in impulsivityno. of participants scoring above BPDSI‐IV3 impulsivity… compared with treatment (low certainty).

1 finding from 1 review

Systems training for emotional predictability and problem solving for borderline personality disorder + individual therapy (STEPPS+IT) vs treatment

Parasuicidalityno. of participants scoring above BPDSI‐IV3 parasuicide cut‐off score · patients with borderline personality disorder

Systems training for emotional predictability and problem solving… showed no clear difference in parasuicidalityno. of participants scoring above BPDSI‐IV3… compared with treatment (low certainty).

1 finding from 1 review

Intervention not reported

Anaemia at end of therapy (total), as defined by trial authors · menstruating women (non‐pregnant women of reproductive age)

The intervention probably leads to lower anaemia at end of therapy (total), as defined by trial authors (moderate certainty).

1 finding from 1 review

Intervention not reported

Iron deficiency at end of therapy (total), as defined by trial authors · menstruating women (non‐pregnant women of reproductive age)

The intervention probably leads to lower iron deficiency at end of therapy (total), as defined by trial authors (moderate certainty).

1 finding from 1 review

BoNT‐A vs usual care or physiotherapy

Instrumented gait analysis (kinematics) (not measured) · children with CP

The review found no eligible studies for this question.

3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Function · children with CP
3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Range of motion (passive ankle dorsiflexion) · children with CP
3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Satisfaction (not measured) · children with CP

The review found no eligible studies for this question.

2 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Spasticity (ankle plantarflexors) · children with CP
3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Adverse events · children with CP

The review found no eligible studies for this question.

3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Gait assessment ‐ not measured · children with CP

The review found no eligible studies for this question.

2 findings from 1 review