Socioeconomic effects · people at increased risk for developing type 2 diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · people at increased risk for developing type 2 diabetes
It is very uncertain whether summary of findings: pioglitazone monotherapy changes all‐cause mortality (N) compared with no intervention (very low certainty).
1 finding from 1 review
Incidence of T2DM (N) · people at increased risk for developing type 2 diabetes
Summary of findings: pioglitazone monotherapy probably leads to lower incidence of T2DM (N) Diagnostic criteria: 9 studies applied the WHO… compared with no intervention (moderate certainty).
1 finding from 1 review
Serious adverse events (N) · people at increased risk for developing type 2 diabetes
Summary of findings: pioglitazone monotherapy showed no clear difference in serious adverse events (N) compared with no intervention (low certainty).
1 finding from 1 review
Cardiovascular mortality · people at increased risk for developing type 2 diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Non‐fatal myocardial infarction/stroke · people at increased risk for developing type 2 diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Health‐related quality of life · people at increased risk for developing type 2 diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Socioeconomic effects · people at increased risk for developing type 2 diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Incidence of T2DM (N) · people at increased risk for developing type 2 diabetes
1 finding from 1 review
no estimate extracted
2 participants
GRADE not reported
Metformin Diagnostic criteria: 2 studies applied the WHO 1999 criteria for 'prediabetes' (FPG > 6.1 mmol/L and < 7.0 mmol/L and/or a 2‐h glucose < 11.1 mmol/L after a 75 g OGTT; Chen 2007a; Zeng 2013) · people at increased risk for developing type 2 diabetes
Summary of findings: pioglitazone monotherapy showed no clear difference in metformin Diagnostic criteria: 2 studies applied the WHO 1999… compared with another pharmacological glucose‐lowering monotherapy (low certainty).
1 finding from 1 review
Acarbose Diagnostic criteria: 1 study applied the WHO 1999 criteria for prediabetes (FPG > 6.1 mmol/L and < 7.0 mmol/L and/or a 2‐h glucose < 11.1 mmol/L after a 75 g OGTT; Chen 2007a) · people at increased risk for developing type 2 diabetes
1 finding from 1 review
Repaglinide Diagnostic criteria: 1 study applied the ADA 2010 criteria (FPG ≥ 5.6 mmol/L and < 6.9 mmol/L and 2‐h glucose ≥ 7.8 mmol/L or < 11.0 mmol/L after a 75 g OGTT; Zhang 2007) · people at increased risk for developing type 2 diabetes
1 finding from 1 review
Serious adverse events (N) · people at increased risk for developing type 2 diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Any perinatal death after randomisation · pregnant women at increased risk of fetal complications
Umbilical artery Doppler ultrasound probably leads to lower any perinatal death after randomisation compared with no Doppler ultrasound (moderate certainty).
1 finding from 1 review
Serious neonatal morbidity · pregnant women at increased risk of fetal complications
1 finding from 1 review
Stillbirth · pregnant women at increased risk of fetal complications
Umbilical artery Doppler ultrasound showed no clear difference in stillbirth compared with no Doppler ultrasound (low certainty).
1 finding from 1 review
Apgar score less than 7 at 5 minutes · pregnant women at increased risk of fetal complications
Umbilical artery Doppler ultrasound showed no clear difference in apgar < 7 at 5 minutes compared with no Doppler ultrasound (low certainty).
1 finding from 1 review
Caesarean section · pregnant women at increased risk of fetal complications
Umbilical artery Doppler ultrasound probably leads to lower caesarean section (elective and emergency) compared with no Doppler ultrasound (moderate certainty).
1 finding from 1 review
Induction of labour · pregnant women at increased risk of fetal complications
Umbilical artery Doppler ultrasound probably leads to lower induction of labour compared with no Doppler ultrasound (moderate certainty).
1 finding from 1 review
Neurodevelopmental outcomes · pregnant women at increased risk of fetal complications
1 finding from 1 review