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Evidence found and GRADE certainty

340 questions · 343 findings · 27 reviews · Musculoskeletal

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No studies found 66 · 19.2%GRADE not reported 25 · 7.3%Very low 64 · 18.7%Low 103 · 30%Moderate 54 · 15.7%High 31 · 9%

Combination of manual therapy and exercise following joint distension vs sham ultrasound following joint distension

Global assessment of treatment success · patients with adhesive capsulitis (frozen shoulder)

Combination of manual therapy and exercise following joint distension leads to higher global assessment of treatment success "Success, much improved,… compared with sham ultrasound following joint distension (high certainty).

1 finding from 1 review

Combination of manual therapy and exercise following joint distension vs sham ultrasound following joint distension

Adverse events · patients with adhesive capsulitis (frozen shoulder)

Combination of manual therapy and exercise following joint distension leads to lower adverse events compared with sham ultrasound following joint distension (high certainty).

1 finding from 1 review

Combination of manual therapy, exercise, electrotherapy and oral NSAID vs oral NSAID

Global assessment of treatment success · patients with adhesive capsulitis (frozen shoulder)

Combination of manual therapy, exercise, electrotherapy and oral NSAID may leads to higher global assessment of treatment success "Disappearance of shoulder… compared with oral NSAID (low certainty).

1 finding from 1 review

Combination of manual therapy, exercise, electrotherapy and oral NSAID vs oral NSAID

Adverse events Pain persisting longer than 2 hours after treatment (during the 3‐week treatment period) · patients with adhesive capsulitis (frozen shoulder)

Combination of manual therapy, exercise, electrotherapy and oral NSAID may leads to higher adverse events Pain persisting longer than 2 hours after treatment… compared with oral NSAID (low certainty).

1 finding from 1 review

Summary of findings table ‐ Progressive resistance exercise interventions vs usual care with or without sham interventions

Functional ability: new incidence of delirium during hospitalisation · acutely hospitalised older medical patients

Summary of findings table ‐ Progressive resistance exercise… showed no clear difference in functional ability: new incidence of delirium during hospitalisation compared with usual care with or without sham interventions (low certainty).

1 finding from 1 review

Summary of findings table ‐ Progressive resistance exercise interventions vs usual care with or without sham interventions

Falls during hospitalisation · acutely hospitalised older medical patients

Summary of findings table ‐ Progressive resistance exercise… showed no clear difference in falls during hospitalisation compared with usual care with or without sham interventions (low certainty).

1 finding from 1 review

Summary of findings table ‐ Progressive resistance exercise interventions vs usual care with or without sham interventions

Medical deterioration during hospitalisation · acutely hospitalised older medical patients

It is very uncertain whether summary of findings table ‐ Progressive resistance exercise… changes medical deterioration during hospitalisation compared with usual care with or without sham interventions (very low certainty).

1 finding from 1 review