Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

370 questions · 377 findings · 26 reviews · Gut

No studies found 103 · 27.3%GRADE not reported 11 · 2.9%Very low 99 · 26.3%Low 75 · 19.9%Moderate 67 · 17.8%High 22 · 5.8%

Budesonide 10 mg vs prednisolone

Adverse event ‐ Reduction in plasma cortisol below lower reference limit · Adult patients with active ulcerative colitis

It is very uncertain whether budesonide 10 mg changes adverse event ‐ Reduction in plasma cortisol below lower reference… compared with prednisolone 40 mg (very low certainty).

1 finding from 1 review

Budesonide vs mesalamine

Remission (combined clinical and endoscopic remission) · Adult patients with active ulcerative colitis

Budesonide showed no clear difference in remission (combined clinical and endoscopic remission) compared with mesalamine (low certainty).

1 finding from 1 review