Findings

What do systematic reviews say?

164 questions · 173 findings · 17 reviews · All outcomes

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No studies found 28 · 16.2%GRADE not reported 115 · 66.5%Very low 30 · 17.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Enamel matrix derivative (EMD; Emdogain) vs Various bone grafting (BG) procedures (animal-derived or synthetic bone / bioactive ceramic filler)

Marginal bone level change · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…

The review found no eligible studies for this question.

1 finding from 1 review

Enamel matrix derivative (Emdogain®) for periodontal tissue regeneration in intrabony defects 2009 · Cochrane All outcomes
1 year (time-points 1, 5 and 10 years planned)
Radiographic bone level: no trial evaluated this.
0 studies
No studies found

Enamel matrix derivative (EMD; Emdogain) vs Various bone grafting (BG) procedures (animal-derived or synthetic bone / bioactive ceramic filler)

Change in probing pocket depth (PPD) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…

1 finding from 1 review

Enamel matrix derivative (Emdogain®) for periodontal tissue regeneration in intrabony defects 2009 · Cochrane All outcomes
1 year (time-points 1, 5 and 10 years planned)
No statistically significant differences (one trial, Leknes 2009).
1 study
GRADE not reported

Enamel matrix derivative (EMD; Emdogain) vs Various bone grafting (BG) procedures (animal-derived or synthetic bone / bioactive ceramic filler)

Tooth loss · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…

1 finding from 1 review

Enamel matrix derivative (Emdogain®) for periodontal tissue regeneration in intrabony defects 2009 · Cochrane All outcomes
1 year (time-points 1, 5 and 10 years planned)
No teeth were lost in either group.
1 study
GRADE not reported

Direct composite resin restoration vs Full-coverage metal-ceramic crown

Clinical failure (post dislodgement) · Participants with endodontically-treated permanent premolars restored with a carbon-fibre post (Category III)

Direct composite restoration (final restoration) showed no clear difference in clinical failure (post dislodgement) compared with full-coverage metal-ceramic crown; GRADE not reported.

1 finding from 1 review

Root canal posts for the restoration of root filled teeth 2007 · Cochrane All outcomes
36 months (3 years); dislodgement assessed at 24 months
RR 1.85 [0.17, 19.8]
1 study · 104 participants
GRADE not reported