Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,036 questions · 1,100 findings · 261 reviews

No studies found 160 · 14.5%GRADE not reported 188 · 17.1%Very low 270 · 24.5%Low 303 · 27.5%Moderate 139 · 12.6%High 40 · 3.6%

Summary of findings table ‐ Remifentanil vs diazepam

Maternal OAA score (observer assessment of alertness/sedation) < 4 (Maternal sedation measured using sedation scores as defined by authors) · health problem or population

Summary of findings table ‐ Remifentanil may leads to lower maternal OAA score (observer assessment of alertness/sedation) < 4… compared with diazepam (low certainty).

1 finding from 1 review

Laser therapy vs no treatment

Scar severity ‐ 585‐nm Pulsed‐Dye Laser (PDL) versus no treatment ‐ patient self‐assessment of scar improvement of 50% or higher ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

Laser therapy may leads to higher scar severity ‐ 585‐nm Pulsed‐Dye Laser (PDL) versus no treatment ‐… compared with no treatment (low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Scar severity ‐ 585‐nm PDL versus TAC ‐ patient self‐assessment of scar improvement of 50% or higher, or patients considering the scar better or much better ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes scar severity ‐ 585‐nm PDL versus TAC ‐ patient self‐assessment of… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Scar severity ‐ 585‐nm PDL versus 5‐FU ‐ patient self‐assessment of scar improvement of 50% or higher ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes scar severity ‐ 585‐nm PDL versus 5‐FU ‐ patient self‐assessment of… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Scar severity ‐ 585‐nm PDL versus TAC plus 5‐FU ‐ patient self‐assessment of scar improvement of 50% or higher ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes scar severity ‐ 585‐nm PDL versus TAC plus 5‐FU ‐ patient… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy vs other treatments

Scar severity ‐ erbium laser versus TAC ‐ patient self‐assessment ‐ patients considering the scar much better ‐ hypertrophic scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes scar severity ‐ erbium laser versus TAC ‐ patient self‐assessment ‐… compared with other treatments (very low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Scar severity ‐ 585‐nm pulsed‐dye laser (PDL) plus triamcinolone acetonide (TAC) plus 5‐Fluorouracil (5‐FU) versus TAC plus 5‐FU ‐ blinded observer assessment of good to excellent scar improvement ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy plus other treatment changes scar severity ‐ 585‐nm pulsed‐dye laser (PDL) plus triamcinolone… compared with other treatment (very low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Scar severity ‐ 585‐nm PDL plus TAC plus 5 FU versus TAC plus 5‐FU ‐ patient self‐assessment of good to excellent scar improvement ‐ hypertrophic and keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy plus other treatment changes scar severity ‐ 585‐nm PDL plus TAC plus 5 FU versus TAC plus 5‐FU ‐… compared with other treatment (very low certainty).

1 finding from 1 review

Laser therapy vs no treatment

Scar severity assessed by health professionals · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy changes scar severity ‐ Non‐Ablative Fractional Laser (NAFL) versus no… compared with no treatment (very low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Scar severity ‐ Neodymium‐doped yttrium aluminium garnet (Nd:YAG) laser plus Diprospan plus 5‐FU versus Diprospan plus 5‐FU ‐ blinded observer assessment of good to excellent scar improvement ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy plus other treatment changes scar severity ‐ Neodymium‐doped yttrium aluminium garnet (Nd:YAG)… compared with other treatment (very low certainty).

1 finding from 1 review

Laser therapy plus other treatment vs other treatment

Scar severity: Nd:YAG laser plus Diprospan plus 5‐FU versus Diprospan plus 5‐FU ‐ patient self‐assessment of scar improvement of 50% or higher ‐ keloid scars ‐ · participants with hypertrophic and keloid scars

It is very uncertain whether laser therapy plus other treatment changes scar severity: Nd:YAG laser plus Diprospan plus 5‐FU versus… compared with other treatment (very low certainty).

1 finding from 1 review

Laser therapy vs no treatment

Scar severity ‐ NAFL versus no treatment ‐ patient global assessment measured on a VAS ranging from 0 to 100 mm (0 = as normal skin and 100 = worst possible scar) ‐ hypertrophic scars ‐ · participants with hypertrophic and keloid scars
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Number of reported cases of child abuse and neglect (professionals' self‐report, actual cases) Time of outcome assessment: short term (3 months postintervention) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Attitudes toward the duty to report child abuse and neglect Measured by: professionals’ self‐reported attitudes towards the duty to report child abuse and neglect Time of outcome assessment: short term (postintervention) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Number of reported cases of child abuse and neglect (professionals' self‐report, hypothetical vignette cases) Time of outcome assessment: short term (postintervention) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Knowledge of reporting duty, processes, and procedures Measured by: professionals' self‐reported knowledge of jurisdictional or institutional reporting duties, or both Time of outcome assessment: short term (postintervention) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review