Findings

What do systematic reviews say?

406 questions · 416 findings · 20 reviews · Common Mental Disorders

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No studies found 73 · 17.5%GRADE not reported 9 · 2.2%Very low 144 · 34.6%Low 123 · 29.6%Moderate 59 · 14.2%High 8 · 1.9%

Exercise therapy vs antidepressants

Fatigue · men and women aged over 18 years with chronic fatigue syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise therapy vs antidepressants

Participants with serious adverse reactions · men and women aged over 18 years with chronic fatigue syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise therapy vs antidepressants

Pain End of treatment and long term · men and women aged over 18 years with chronic fatigue syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise therapy vs antidepressants

Physical functioning End of treatment and long term · men and women aged over 18 years with chronic fatigue syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise therapy vs antidepressants

QoL · men and women aged over 18 years with chronic fatigue syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise therapy vs antidepressants

Depression Measured at end of treatment, 26 weeks · men and women aged over 18 years with chronic fatigue syndrome

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 48 participants
Very low

Exercise therapy vs antidepressants

Depression Long term · men and women aged over 18 years with chronic fatigue syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise therapy vs antidepressants

Sleep · men and women aged over 18 years with chronic fatigue syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Psychological therapies vs tricyclic antidepressants (TCAs)

Short‐term improvement Scale used (range; lower is better): Clinical Global Impression (1 to 7) Agoraphobic Cognitions Questionnaire (1 to 70) Panic Disorder Severity Scale (0 to 28) Brief Scale for Anxiety (0 to 60) · adults with panic disorder

1 finding from 1 review

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 414 participants
Moderate

Psychological therapies vs other antidepressants

Short‐term remission · adults with panic disorder

It is very uncertain whether all psychological therapies changes short‐term remission compared with other antidepressants (very low certainty).

1 finding from 1 review

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
RR 0.9 [0.48, 1.67]
3 studies · 135 participants
Very low

Psychological therapies vs other antidepressants

Short‐term response · adults with panic disorder

All psychological therapies showed no clear difference in short‐term response compared with other antidepressants (low certainty).

1 finding from 1 review

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
RR 0.96 [0.67, 1.37]
3 studies · 128 participants
Low

Psychological therapies vs other antidepressants

Leaving the study early · adults with panic disorder

All psychological therapies showed no clear difference in dropouts for any reason compared with other antidepressants (low certainty).

1 finding from 1 review

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
RR 1.55 [0.91, 2.65]
3 studies · 180 participants
Low

Psychological therapies vs other antidepressants

Long‐term remission/response · adults with panic disorder

1 finding from 1 review

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Psychological therapies vs other antidepressants

Short‐term improvement Scale used (range; lower is better): Panic Disorder Severity Scale (0 to 28) Symptom Checklist‐90‐Revised Global Severity · adults with panic disorder

1 finding from 1 review

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 27 participants
Moderate

Psychological therapies vs antidepressants alone or antidepressants and benzodiazepines

Short‐term remission · adults with panic disorder

All psychological therapies showed no clear difference in short‐term remission compared with antidepressants alone or antidepressants and benzodiazepines (low certainty).

1 finding from 1 review

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
RR 0.86 [0.71, 1.05]
11 studies · 663 participants
Low

Psychological therapies vs antidepressants alone or antidepressants and benzodiazepines

Short‐term response · adults with panic disorder

All psychological therapies showed no clear difference in short‐term response compared with antidepressants alone or antidepressants and benzodiazepines (low certainty).

1 finding from 1 review

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
RR 0.95 [0.76, 1.18]
12 studies · 800 participants
Low

Psychological therapies vs antidepressants alone or antidepressants and benzodiazepines

Leaving the study early · adults with panic disorder

It is very uncertain whether all psychological therapies changes dropouts for any reason compared with antidepressants alone or antidepressants and benzodiazepines (very low certainty).

1 finding from 1 review

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
RR 1.08 [0.77, 1.51]
13 studies · 909 participants
Very low

Psychological therapies vs antidepressants alone or antidepressants and benzodiazepines

Long‐term remission/response · adults with panic disorder

1 finding from 1 review

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Psychological therapies vs antidepressants alone or antidepressants and benzodiazepines

Short‐term improvement Scale used (range; lower is better): panic frequency Clinical Global Impression (1 to 7) Agoraphobic Cognitive Questionnaire (1 to 70) Fear Questionnaire Agoraphobia Subscale (0 to 14) Brief Scale for Anxiety (0 to 60) STAI ... · adults with panic disorder

1 finding from 1 review

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 638 participants
Low

Psychological therapies vs tricyclic antidepressants (TCAs)

Short‐term remission · adults with panic disorder

All psychological therapies showed no clear difference in short‐term remission compared with tricyclic antidepressants (low certainty).

1 finding from 1 review

Psychological therapies versus pharmacological interventions for panic disorder with or without agoraphobia in adults 2016 · Cochrane Headline outcomes only
RR 0.82 [0.62, 1.09]
3 studies · 229 participants
Low