Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

175 questions · 179 findings · 31 reviews

No studies found 46 · 25.7%GRADE not reported 60 · 33.5%Very low 41 · 22.9%Low 19 · 10.6%Moderate 11 · 6.1%High 2 · 1.1%

Low molecular weight heparin vs unfractionated heparin

Microvascular insufficiency due to vessel occlusion ‐ venous occlusion (analysed by participant, · patients undergoing digital replantation after traumatic amputation

It is very uncertain whether low molecular weight heparin changes microvascular insufficiency due to vessel occlusion ‐ venous… compared with unfractionated heparin (very low certainty).

1 finding from 1 review

PAAP vs no PAAP

Rate of exacerbations requiring emergency department treatment or admission · adults with asthma

PAAP showed no clear difference in exacerbation requiring ED or hospitalisation. compared with no PAAP (low certainty).

1 finding from 1 review

PAAP vs no PAAP

Serious adverse events (including mortality) · adults with asthma

It is very uncertain whether PAAP changes serious adverse events (including deaths). compared with no PAAP (very low certainty).

1 finding from 1 review

PAAP vs no PAAP

Rate of exacerbations requiring systemic corticosteroids · adults with asthma

It is very uncertain whether PAAP changes exacerbation requiring OCS. compared with no PAAP (very low certainty).

1 finding from 1 review