Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

291 questions · 293 findings · 75 reviews

No studies found 56 · 19.1%GRADE not reported 24 · 8.2%Very low 61 · 20.8%Low 62 · 21.2%Moderate 39 · 13.3%High 51 · 17.4%

Long‐term red cell transfusion vs usual care

Proportion of participants developing new or progressive SCI lesions · prevention of SCI in people with SCD and abnormal TCD velocities

Long‐term RBC transfusion may leads to lower proportion of participants developing new or progressive SCI lesions compared with standard care (low certainty).

1 finding from 1 review

Intervention not reported

Cerivastatin dose · participants with normal or abnormal lipid profiles

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

0.05 mg/d · participants with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

0.1 mg/d · participants with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

0.2 mg/d · participants with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

0.3 mg/d · participants with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

0.4 mg/d · participants with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

0.8 mg/d · participants with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

CI: confidence interval · participants with normal or abnormal lipid profiles

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

aMean baseline values. · participants with normal or abnormal lipid profiles

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Cerivastatin dose · participants with normal or abnormal lipid profiles

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

0.05 mg/d · participants with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

0.05 mg/d · participants with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

0.1 mg/d · participants with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

0.2 mg/d · participants with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

0.3 mg/d · participants with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

0.4 mg/d · participants with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

0.8 mg/d · participants with normal or abnormal lipid profiles
1 finding from 1 review