Quality of life or psychological well‐being (higher = higher quality of life or psychological well‐being): end‐of‐intervention · older people with depression
1 finding from 1 review
Anxious symptomatology (lower = less anxious symptomatology): end‐of‐intervention · older people with depression
1 finding from 1 review
Change in eGFR · preventing the progression of CKD
1 finding from 1 review
Serious adverse events ( · preventing the progression of CKD
Metformin showed no clear difference in serious adverse events ( compared with active control (moderate certainty).
1 finding from 1 review
Withdrew due to intolerance ( · preventing the progression of CKD
Metformin showed no clear difference in withdrew due to intolerance ( compared with active control (moderate certainty).
1 finding from 1 review
Dosing and tolerance ( · preventing the progression of CKD
1 finding from 1 review
Kidney failure · preventing the progression of CKD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
UACR (% change) ( · preventing the progression of CKD
1 finding from 1 review
All‐cause death ( · preventing the progression of CKD
It is very uncertain whether metformin changes all‐cause death ( compared with placebo (very low certainty).
1 finding from 1 review
Serious adverse events ( · preventing the progression of CKD
Metformin showed no clear difference in serious adverse events ( compared with placebo (moderate certainty).
1 finding from 1 review
Withdrew due to intolerance ( · preventing the progression of CKD
Metformin probably leads to higher withdrew due to intolerance ( compared with placebo (moderate certainty).
1 finding from 1 review
Dose tolerability ( · preventing the progression of CKD
1 finding from 1 review
Kidney failure · preventing the progression of CKD
It is very uncertain whether metformin changes kidney failure (median compared with placebo (very low certainty).
1 finding from 1 review
Change in proteinuria (1 year) · preventing the progression of CKD
1 finding from 1 review
Change in eGFR · preventing the progression of CKD
1 finding from 1 review
All‐cause death ( · preventing the progression of CKD
Metformin showed no clear difference in all‐cause death ( compared with active control (low certainty).
1 finding from 1 review
Maternal anaemia · pregnant women
It is very uncertain whether summary of findings table ‐ Vitamin B12 supplementation changes maternal anaemia compared with placebo/no vitamin B12 supplementation (very low certainty).
1 finding from 1 review
Maternal vitamin B12 deficiency · pregnant women
It is very uncertain whether summary of findings table ‐ Vitamin B12 supplementation changes maternal vitamin B12 deficiency compared with placebo/no vitamin B12 supplementation (very low certainty).
1 finding from 1 review
Miscarriage and spontaneous abortion · pregnant women
1 finding from 1 review
Low birthweight · pregnant women
Summary of findings table ‐ Vitamin B12 supplementation showed no clear difference in low birthweight (< 2500 g) compared with placebo/no vitamin B12 supplementation (low certainty).
1 finding from 1 review