Chinese herbal medicines vs drugs
Overall severity score (Analysis 1.3) Clinician's rating. Scale from 1 to 80 · atopic eczema
1 finding from 1 review
- no estimate extracted15 studies · 1062 participantsLow
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What do systematic reviews say?
1,835 questions · 1,886 findings · 74 reviews · Skin
No studies found 542 · 28.7%GRADE not reported 130 · 6.9%Very low 326 · 17.3%Low 434 · 23%Moderate 348 · 18.5%High 106 · 5.6%
Chinese herbal medicines vs drugs
Adverse events (Analysis 1.7) Participant's report · atopic eczema
CHM may leads to lower adverse events (Analysis 2.6) Participant's reports compared with drugs (low certainty).
1 finding from 1 review
- RR 0.44 [0.32, 0.61]15 studies · 1396 participantsLow
Combination of oral and topical CHM vs same oral CHM
Total effectiveness rate (Analysis 1.1) Clinician's rating · atopic eczema
Combination of oral and topical CHM showed no clear difference in total effectiveness rate (Analysis 3.1) Clinician's rating compared with same oral CHM (low certainty).
1 finding from 1 review
- RR 1.13 [0.78, 1.63]1 study · 20 participantsLow
Combination of oral and topical CHM vs same oral CHM
Overall severity score (Analysis 1.3) Clinician's rating. Scale from 1 to 80 · atopic eczema
1 finding from 1 review
- no estimate extracted1 study · 20 participantsLow
Combination of oral and topical CHM vs same oral CHM
QoL · atopic eczema
1 finding from 1 review
- no estimate extracted1 study · 20 participantsLow
Combination of oral and topical CHM vs same oral CHM
Adverse events (Analysis 1.7) Participant's report · atopic eczema
Combination of oral and topical CHM showed no clear difference in adverse events (Analysis 3.7) Participant's report compared with same oral CHM (low certainty).
1 finding from 1 review
- RR 1 [0.07, 13.87]1 study · 20 participantsLow
Combination of oral and topical CHM vs same oral CHM
Itching VAS (Analysis 1.2) Participant's rating. Scale from 1 to 10 · atopic eczema
1 finding from 1 review
- no estimate extracted1 study · 22 participantsLow
Combination of oral and topical CHM vs same oral CHM
Skin lesion score (Analysis 3.4) Clinician's rating. Scale from 0 to 24 · atopic eczema
1 finding from 1 review
- no estimate extracted1 study · 22 participantsLow
Chinese herbal medicines vs placebo
Itching VAS (Analysis 1.2) Participant's rating. Scale from 1 to 10 · atopic eczema
1 finding from 1 review
- no estimate extracted2 studies · 94 participantsLow
Chinese herbal medicines vs placebo
Overall severity score (Analysis 1.3) Clinician's rating. Scale from 1 to 80 · atopic eczema
1 finding from 1 review
- no estimate extracted4 studies · 239 participantsVery low
Chinese herbal medicines vs placebo
QoL · atopic eczema
1 finding from 1 review
- no estimate extracted1 study · 85 participantsModerate
Chinese herbal medicines vs placebo
Adverse events (Analysis 1.7) Participant's report · atopic eczema
CHM showed no clear difference in adverse events (Analysis 1.7) Participant's report compared with placebo (low certainty).
1 finding from 1 review
- RR 0.71 [0.06, 8.67]2 studies · 129 participantsLow
Chinese herbal medicines vs drugs
Total effectiveness rate (Analysis 1.1) Clinician's rating · atopic eczema
It is very uncertain whether CHM changes total effectiveness rate (Analysis 2.1) Clinician's rating compared with drugs (very low certainty).
1 finding from 1 review
- RR 1.43 [1.27, 1.61]21 studies · 1868 participantsVery low
Chinese herbal medicines vs drugs
Total effectiveness rate with subgroup analysis ‐ individualised treatment Clinician's rating · atopic eczema
CHM may leads to higher total effectiveness rate with subgroup analysis ‐ individualised… compared with drugs (low certainty).
1 finding from 1 review
- RR 1.5 [1.3, 1.74]7 studies · 567 participantsLow
Chinese herbal medicines vs drugs
Total effectiveness rate with subgroup analysis ‐ non‐individualised treatment Clinician's rating · atopic eczema
It is very uncertain whether CHM changes total effectiveness rate with subgroup analysis ‐ non‐individualised… compared with drugs (very low certainty).
1 finding from 1 review
- RR 1.37 [1.17, 1.6]14 studies · 1301 participantsVery low
Chinese herbal medicines vs drugs
Itching VAS (Analysis 1.2) Participant's rating. Scale from 1 to 10 · atopic eczema
1 finding from 1 review
- no estimate extracted7 studies · 465 participantsLow
Intervention not reported
First recurrence · high‐risk melanoma participants
The intervention leads to lower first recurrence (high certainty).
1 finding from 1 review
- Interferon alpha for the adjuvant treatment of cutaneous melanoma 2013 · Cochrane Headline outcomes onlyHR 0.83 [0.78, 0.87]17 studies · 10345 participantsHigh
Intervention not reported
Death · high‐risk melanoma participants
The intervention leads to lower death (high certainty).
1 finding from 1 review
- Interferon alpha for the adjuvant treatment of cutaneous melanoma 2013 · Cochrane Headline outcomes onlyHR 0.91 [0.85, 0.97]15 studies · 9927 participantsHigh
NB‐UVB vs oral PUVA
Participant‐rated global improvement · people with chronic plaque psoriasis
1 finding from 1 review
- Narrow‐band ultraviolet B phototherapy versus broad‐band ultraviolet B or psoralen‐ultraviolet A photochemotherapy for… 2013 · Cochrane Headline outcomes onlyno estimate extracted0 studies · 0 participantsGRADE not reported
NB‐UVB vs topical PUVA
Percentage of participants reaching PASI 75 · People with palmoplantar psoriasis
1 finding from 1 review
- Narrow‐band ultraviolet B phototherapy versus broad‐band ultraviolet B or psoralen‐ultraviolet A photochemotherapy for… 2013 · Cochrane Headline outcomes onlyno estimate extracted0 studies · 0 participantsGRADE not reported