Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,327 questions · 2,494 findings · 87 reviews · All outcomes

No studies found 450 · 18%GRADE not reported 1,487 · 59.6%Very low 385 · 15.4%Low 121 · 4.9%Moderate 50 · 2%High 1 · 0%

Prophylactic systemic antibiotics (amoxicillin) vs placebo or no antibiotic

Postoperative infection · Adults undergoing dental implant placement

Prophylactic systemic antibiotics (amoxicillin) showed no clear difference in postoperative infection compared with no antibiotics or placebo; GRADE not reported.

1 finding from 1 review

Two miniplates (transbuccal approach) vs One miniplate plus two screws (intraoral approach at external oblique ridge)

Restoration of function (malocclusion) · Adults with fractures of the mandibular angle

Two miniplates (transbuccal approach) showed no clear difference in restoration of function (malocclusion) compared with one miniplate plus two screws (intraoral approach at external…; GRADE not reported.

1 finding from 1 review

Zygomatic implants without bone grafts (as a complete alternative to any bone augmentation procedure) vs Conventional dental implants in augmented maxillae

Implant failure rate · Participants with an atrophic maxilla who cannot be rehabilitated with conventional dental implants due to lack of bone (including…

The review found no eligible studies for this question.

1 finding from 1 review

Primary school-based behavioural intervention (both oral hygiene and dietary components) vs No treatment (or delayed treatment)

Frequency of cariogenic food and drink consumption · Children aged 4 to 12 years attending primary school
1 finding from 1 review

Immediate mobilization vs 2 weeks delayed mobilization (IMF)

Average pain scores (0-100 VAS) · Adults with mandibular fractures excluding condyles (fixed with 2 mm titanium miniplates)
1 finding from 1 review
  • Pain (scale 1 to 10) was minor in both groups with no significant differences (Table 4): 6 weeks 1.55 vs 1.20; 3 months 1.00 vs 2.64; 6 months 1.30 vs 2.71 (immediate release vs IMF). 95% confidence interval not…
    1 study
    GRADE not reported

Primary school-based behavioural intervention (both oral hygiene and dietary components) vs No treatment (or delayed treatment)

Frequency of toothbrushing · Children aged 4 to 12 years attending primary school
1 finding from 1 review

Locking plate vs 2 mm non-locking titanium plates

Drop-out rate due to protocol deviation · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement
1 finding from 1 review
  • Early premature removal of IMF (from hours up to 2 weeks) was reported in 13 of the 90 participants analysed (Collins 2004); participants released their own IMF or reported that "the wires fell off".
    1 study · 90 participants
    GRADE not reported

2 mm titanium plates vs 2.5 mm bioresorbable plates

Post-operative pain (residual pain, any severity) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement

2 mm titanium plates showed no clear difference in post-operative pain (residual pain, any severity) compared with 2.5 mm bioresorbable plates; GRADE not reported.

1 finding from 1 review

Electrostimulation (device) vs Placebo (sham/placebo device)

Unstimulated whole saliva (UWS) · Adults with dry mouth due to Sjogren's Syndrome

It is very uncertain whether electrostimulation (device) changes unstimulated whole saliva (UWS) compared with placebo (sham/placebo device) (very low certainty).

1 finding from 1 review

Acupuncture vs sham

Adverse events · Adults with dry mouth due to radiotherapy (head and neck cancer) or Sjogren's Syndrome
1 finding from 1 review

Immediate mobilization vs 2 weeks delayed mobilization (IMF)

Post-operative adverse events and complications · Adults with mandibular fractures excluding condyles (fixed with 2 mm titanium miniplates)
1 finding from 1 review
  • One wound separation and one infection in the immediate-mobilization group. Inferior alveolar nerve status (scale 1 to 3) showed no significant difference at 6 weeks (P=0.76), 3 months (P=0.87) or 6 months (P=0.99).…
    1 study
    GRADE not reported

Hyperbaric oxygen vs No HBO therapy

Cost‐effectiveness · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants

The review found no eligible studies for this question.

1 finding from 1 review