What do systematic reviews say?

Metal-free FDPs (zirconia ceramic) vs Metal-ceramic FDPs

• Metal‐free materials for fixed prosthodontic restorations 2017 · Cochrane All outcomes

  12 and 36 months
  At 12 months and at 36 months 34 participants were available for analysis. No FDP failure was reported in either treatment approach at either time.
  1 study · 34 participants
  Very low

Metal-free implant-supported FDPs (zirconia-toughened alumina; In-Ceram Zirconia) vs Metal-free implant-supported FDPs (yttria-stabilized tetragonal zirconia; Denzir)

It is very uncertain whether metal-free implant-supported FDPs (zirconia-toughened alumina;… changes bridge complications compared with metal-free implant-supported FDPs (yttria-stabilized tetragonal… (very low certainty).

• Metal‐free materials for fixed prosthodontic restorations 2017 · Cochrane All outcomes

  60 months
  OR 0.02 [0.00, 0.42]
  1 study · 18 participants
  Very low
• Metal‐free materials for fixed prosthodontic restorations 2017 · Cochrane All outcomes

  36 months
  OR 0.02 [0.00, 0.30]
  1 study · 18 participants
  Very low
• Metal‐free materials for fixed prosthodontic restorations 2017 · Cochrane All outcomes

  12 months
  OR 0.04 [0.00, 0.48]
  1 study · 18 participants
  Very low

Metal-free cantilevered FDPs (feldspathic-veneered zirconia) vs Metal-ceramic cantilevered FDPs

Metal-free cantilevered FDPs (feldspathic-veneered zirconia) showed no clear difference in plaque index (PI) compared with metal-ceramic cantilevered FDPs; GRADE not reported.

• Metal‐free materials for fixed prosthodontic restorations 2017 · Cochrane All outcomes

  24 months
  MD -0.10 [-1.04, 0.84]
  1 study · 19 participants
  GRADE not reported

Metal-free cantilevered FDPs (feldspathic-veneered zirconia) vs Metal-ceramic cantilevered FDPs

• Metal‐free materials for fixed prosthodontic restorations 2017 · Cochrane All outcomes

  12, 24 and 36 months
  At 12 months 19 participants were available; no failure and no complication were reported in either group. No failure was reported at 24 or 36 months.
  1 study · 19 participants
  Very low

Metal-free cantilevered FDPs (feldspathic-veneered zirconia) vs Metal-ceramic cantilevered FDPs

Metal-free cantilevered FDPs (feldspathic-veneered zirconia) showed no clear difference in gingival index (GI) compared with metal-ceramic cantilevered FDPs; GRADE not reported.

• Metal‐free materials for fixed prosthodontic restorations 2017 · Cochrane All outcomes

  24 months
  MD 0.03 [-0.75, 0.81]
  1 study · 19 participants
  GRADE not reported

Metal-free tooth-supported FDPs (pressed veneering ceramic) vs Metal-free tooth-supported FDPs (layered veneering ceramic)

• Metal‐free materials for fixed prosthodontic restorations 2017 · Cochrane All outcomes
  No comparative data were presented with regard to aesthetics. Aesthetics evaluated by the patient was reported dichotomously (yes/no) in the trial but no between-group estimate was presented.
  1 study
  GRADE not reported

Metal-free tooth-supported FDPs (pressed veneering ceramic) vs Metal-free tooth-supported FDPs (layered veneering ceramic)

• Metal‐free materials for fixed prosthodontic restorations 2017 · Cochrane All outcomes
  No comparative data were presented for the pre-specified secondary outcomes. The trial analyzed and reported plaque index, bleeding on probing and pocket probing depth but no between-group estimate was presented in the…
  1 study
  GRADE not reported

Metal-free FDPs (zirconia ceramic) vs Metal-ceramic FDPs

The review found no eligible studies for this question.

• Metal‐free materials for fixed prosthodontic restorations 2017 · Cochrane All outcomes
  No data were presented for any of the pre-specified secondary outcomes. The trial registered pocket depth, bleeding on probing and mobility at follow-up visits but did not report the data.
  0 studies
  No studies found

Metal-free cantilevered FDPs (feldspathic-veneered zirconia) vs Metal-ceramic cantilevered FDPs

It is very uncertain whether metal-free cantilevered FDPs (feldspathic-veneered zirconia) changes cantilevered bridge complications compared with metal-ceramic cantilevered FDPs (very low certainty).

• Metal‐free materials for fixed prosthodontic restorations 2017 · Cochrane All outcomes

  24 months
  OR 5.59 [0.23, 133.61]
  1 study · 19 participants
  Very low
• Metal‐free materials for fixed prosthodontic restorations 2017 · Cochrane All outcomes

  36 months
  OR 2.00 [0.15, 26.73]
  1 study · 19 participants
  Very low

Metal-free FDPs (lithium disilicate) vs Metal-ceramic FDPs

It is very uncertain whether metal-free FDPs (lithium disilicate) changes bridge complications compared with metal-ceramic FDPs (very low certainty).

• Metal‐free materials for fixed prosthodontic restorations 2017 · Cochrane All outcomes

  72 months
  OR 0.07 [0.01, 0.75]
  1 study · 22 participants
  Very low

Metal-free implant-supported FDPs (zirconia-toughened alumina; In-Ceram Zirconia) vs Metal-free implant-supported FDPs (yttria-stabilized tetragonal zirconia; Denzir)

• Metal‐free materials for fixed prosthodontic restorations 2017 · Cochrane All outcomes

  12, 36, 60 and 120 months
  No FDP failures were reported in either group at 12, 36, 60 or 120 months (18 participants; 17 at 120 months).
  1 study · 18 participants
  Very low

Metal-free implant-supported FDPs (zirconia-toughened alumina; In-Ceram Zirconia) vs Metal-free implant-supported FDPs (yttria-stabilized tetragonal zirconia; Denzir)

The review found no eligible studies for this question.

• Metal‐free materials for fixed prosthodontic restorations 2017 · Cochrane All outcomes
  No data were presented with regard to aesthetics.
  0 studies
  No studies found

Metal-free tooth-supported FDPs (pressed veneering ceramic) vs Metal-free tooth-supported FDPs (layered veneering ceramic)

• Metal‐free materials for fixed prosthodontic restorations 2017 · Cochrane All outcomes

  12 and 36 months
  At 12 months 40 participants were available and at 36 months 36 participants were available. No FDP failures were reported in either group at either time.
  1 study · 40 participants
  Very low

Metal-free FDPs (lithium disilicate) vs Metal-ceramic FDPs

It is very uncertain whether metal-free FDPs (lithium disilicate) changes bridge failure compared with metal-ceramic FDPs (very low certainty).

• Metal‐free materials for fixed prosthodontic restorations 2017 · Cochrane All outcomes

  72 months
  OR 6.86 [0.66, 71.72]
  1 study · 22 participants
  Very low
• Metal‐free materials for fixed prosthodontic restorations 2017 · Cochrane All outcomes

  12 months
  OR 9.00 [0.96, 84.50]
  1 study · 37 participants
  Very low

Intervention not reported

• Interventions to improve hand hygiene compliance in patient care 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 1 participants
  Moderate

Intervention not reported

The review found no eligible studies for this question.

• Interventions to improve hand hygiene compliance in patient care 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The review found no eligible studies for this question.

• Interventions to improve hand hygiene compliance in patient care 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intracervical vs combined intracervical and paracervical anaesthesia

• Pain relief for outpatient hysteroscopy 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 84 participants
  Very low

Intracervical vs combined intracervical and paracervical anaesthesia

• Pain relief for outpatient hysteroscopy 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 84 participants
  Very low

Intracervical vs combined intracervical and paracervical anaesthesia

• Pain relief for outpatient hysteroscopy 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 84 participants
  Very low