Cure · people with infective endocarditis due to methicillin‐resistant Staphylococcus aureus
It is very uncertain whether fosfomycin plus imipenem changes cure compared with vancomycin (very low certainty).
1 finding from 1 review
RR 0.5 [0.07, 3.55]
1 study · 8 participants
Very low
Adverse events · people with infective endocarditis due to methicillin‐resistant Staphylococcus aureus
It is very uncertain whether fosfomycin plus imipenem changes adverse events compared with vancomycin (very low certainty).
1 finding from 1 review
RR 1 [0.25, 4]
1 study · 8 participants
Very low
Congestive heart failure · people with infective endocarditis due to methicillin‐resistant Staphylococcus aureus
It is very uncertain whether fosfomycin plus imipenem changes congestive heart failure compared with vancomycin (very low certainty).
1 finding from 1 review
RR 9 [0.64, 126.85]
1 study · 8 participants
Very low
Septic embolism · people with infective endocarditis due to methicillin‐resistant Staphylococcus aureus
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Need for cardiac surgical interventions · people with infective endocarditis due to methicillin‐resistant Staphylococcus aureus
It is very uncertain whether fosfomycin plus imipenem changes need for cardiac surgical interventions compared with vancomycin (very low certainty).
1 finding from 1 review
RR 2 [0.28, 14.2]
1 study · 8 participants
Very low
Uncontrolled infection · people with infective endocarditis due to methicillin‐resistant Staphylococcus aureus
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality during hospital stay and all‐cause mortality at 1 year · people with endocarditis on the left side of the heart (on native or prosthetic valves) with bacteraemia for Streptococcus, Enterococcus…
It is very uncertain whether partial oral treatment changes all‐cause mortality during hospital stay and all‐cause mortality at… compared with conventional intravenous treatment of endocarditis on the left side… (very low certainty).
1 finding from 1 review
Cure · people with endocarditis on the left side of the heart (on native or prosthetic valves) with bacteraemia for Streptococcus, Enterococcus…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · people with endocarditis on the left side of the heart (on native or prosthetic valves) with bacteraemia for Streptococcus, Enterococcus…
Partial oral treatment showed no clear difference in adverse events compared with conventional intravenous treatment of endocarditis on the left side… (low certainty).
1 finding from 1 review
Congestive heart failure · people with endocarditis on the left side of the heart (on native or prosthetic valves) with bacteraemia for Streptococcus, Enterococcus…
It is very uncertain whether partial oral treatment changes congestive heart failure compared with conventional intravenous treatment of endocarditis on the left side… (very low certainty).
1 finding from 1 review
Congestive heart failure · people with endocarditis caused by Staphylococcus aureus
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Need for cardiac surgical interventions · people with endocarditis on the left side of the heart (on native or prosthetic valves) with bacteraemia for Streptococcus, Enterococcus…
It is very uncertain whether partial oral treatment changes need for cardiac surgicalinterventions compared with conventional intravenous treatment of endocarditis on the left side… (very low certainty).
1 finding from 1 review
Septic embolism · people with endocarditis on the left side of the heart (on native or prosthetic valves) with bacteraemia for Streptococcus, Enterococcus…
It is very uncertain whether partial oral treatment changes septic embolism compared with conventional intravenous treatment of endocarditis on the left side… (very low certainty).
1 finding from 1 review
Uncontrolled infection · people with endocarditis on the left side of the heart (on native or prosthetic valves) with bacteraemia for Streptococcus, Enterococcus…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Septic embolism4 · people with endocarditis caused by Staphylococcus aureus
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Need for cardiac surgical interventions · people with endocarditis caused by Staphylococcus aureus
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Uncontrolled infection4 · people with endocarditis caused by Staphylococcus aureus
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Clinical cure according to criteria established by study authors Mild‐moderate PID · women with PID
It is very uncertain whether regimens containing macrolides (azithromycin) changes clinical cure according to criteria established by study authors… compared with regimens containing tetracycline (doxycycline) (very low certainty).
2 findings from 1 review
RR 1.18 [0.89, 1.55]
Studies not reported
Very low
RR 1.35 [1.1, 1.67]
Studies not reported
Moderate
Clinical cure according to criteria established by study authors Severe PID · women with PID
Regimens containing quinolone showed no clear difference in clinical cure according to criteria established by study authors… compared with regimens containing cephalosporins (low certainty).
1 finding from 1 review
RR 1.06 [0.91, 1.23]
Studies not reported
Low
Microbiological clearance · women with PID
It is very uncertain whether regimens containing quinolone changes microbiological clearance compared with regimens containing cephalosporins (very low certainty).
1 finding from 1 review
RR 0.95 [0.84, 1.08]
Studies not reported
Very low