Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis and closed (mature) root apex due to carious pulp exposure
In closed-apex teeth, pooled pulpotomy success was 83% (95% CI 69-91%); significantly lower than open apex (z=2.33, p=0.02); ungraded.
1 finding from 1 review
Restoration failure · Children with carious primary teeth
No comparative effect estimate was reported; no bevel had twice the failure rate in the review narrative.
1 finding from 1 review
Restoration failure · Children with carious primary teeth
No comparative effect estimate was reported; the review reports this three-arm comparison but tabulates only compomer failure.
1 finding from 1 review
Restoration failure · Children with carious primary teeth
No comparative effect estimate was reported; failure rates were 3.3% and 15%.
1 finding from 1 review
Restoration failure · Children with carious primary teeth
No comparative effect estimate was reported; etch-and-rinse had a higher tabulated failure rate.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis due to carious pulp exposure
MTA had a significantly higher pulpotomy success rate than calcium hydroxide (indirect comparison; numeric estimate not available); ungraded.
1 finding from 1 review
Restoration failure · Children with carious primary teeth
No comparative effect estimate was reported; tabulated failure rates ranged from 0% to 2.9%.
1 finding from 1 review
Restoration failure · Children with carious primary teeth
No comparative effect estimate was reported; glass carbomer had the highest tabulated failure range.
1 finding from 1 review
Treatment failure (annual failure rate) · Children with previously unrestored, vital carious lesions in primary teeth (no pulp therapy); aged 1.5-11 years
Glass carbomer had very high failure rates (up to 46.2%) in a single RCT, far worse than composite resin or RMGIC; low quality of evidence (ungraded).
1 finding from 1 review
Restoration failure · Children with carious primary teeth
No comparative effect estimate was reported; metal-reinforced GIC had the highest failure rate.
1 finding from 1 review
Restoration failure · Children with carious primary teeth
No comparative effect estimate was reported; the review states cavity conditioner did not improve success.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Human permanent teeth with symptomatic irreversible pulpitis due to carious pulp exposure
In symptomatic irreversible pulpitis, pooled pulpotomy success was 84% (95% CI 72-92%); not significantly different from asymptomatic (z=-1.34, p=0.18); ungraded.
1 finding from 1 review
Restoration failure · Children with carious primary teeth
No comparative effect estimate was reported; failure rates were tabulated.
1 finding from 1 review
Treatment failure (annual failure rate) · Children with carious primary molars treated by pulpotomy (vital pulp therapy)
Preformed metal crowns had a low annual failure rate (2.4%) in primary molars after pulpotomy, lower than amalgam in the same trial (single high-risk-of-bias RCT; low quality of evidence; not GRADE-rated).
2 findings from 1 review
Restoration failure · Children with carious primary teeth
No comparative effect estimate was reported; bilayer placement and nanofilled coating were described as improving survival.
1 finding from 1 review
Annual failure rate (%) 32.4%, 13.7%, 18.7%, 13.4% by insertion/coating arm
1 study · 208 participants
GRADE not reported
Tooth survival · Children with carious vital pulp exposure in primary incisors
Tooth survival was reported narratively in two trials and was not pooled.
1 finding from 1 review
Intervention not reported
Clinical and radiographic success
1 finding from 1 review
no estimate extracted
1 study
GRADE not reported
Overall success (composite of clinical and radiographic success) · Immature (young) permanent teeth with open apex and vital pulp exposed to dental caries or trauma, in children aged 6-14 years
A single RCT found no difference in pulpotomy success between MTA and platelet-rich fibrin (both 100% through 24 months; not pooled; ungraded).
1 finding from 1 review
Single RCT (Keswani 2014, 62 teeth): 100% clinical and radiographic success in both MTA and PRF at 6, 12 and 24 months (MTA 29/29, 27/27, 26/26; PRF 30/30, 29/29, 27/27); no difference between groups; not pooled
1 study · 62 participants
GRADE not reported
Overall success (composite of clinical and radiographic success) · Immature (young) permanent teeth with open apex and vital pulp exposed to dental caries or trauma, in children aged 6-14 years
MTA and calcium hydroxide had similar clinical and radiographic pulpotomy success at 6 months (RR 1.00, 95% CI 0.94 to 1.06; 2 RCTs; ungraded).
2 findings from 1 review
Overall success (composite of clinical and radiographic success) · Immature (young) permanent teeth with open apex and vital pulp exposed to dental caries or trauma, in children aged 6-14 years
A single RCT found no difference in pulpotomy success between MTA and calcium-enriched mixture (both 100% at 6 and 12 months; not pooled; ungraded).
1 finding from 1 review
Single RCT (Nosrat 2012, 118 roots): 100% clinical and radiographic success in both MTA and CEM at 6 and 12 months (MTA 53/53 then 54/54 roots; CEM 55/55 then 57/57 roots); no statistical difference between groups at…
1 study · 118 participants
GRADE not reported