Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

573 questions · 674 findings · 44 reviews · All outcomes

No studies found 253 · 37.5%GRADE not reported 258 · 38.3%Very low 106 · 15.7%Low 38 · 5.6%Moderate 15 · 2.2%High 4 · 0.6%

Two miniplates (transbuccal approach) vs One miniplate plus two screws (intraoral approach at external oblique ridge)

Requirement for additional (surgical) interventions (plate removal) · Adults with fractures of the mandibular angle

Two miniplates (transbuccal approach) showed no clear difference in requirement for additional (surgical) interventions (plate removal) compared with one miniplate plus two screws (intraoral approach at external…; GRADE not reported.

1 finding from 1 review

2 mm titanium plates vs 2.5 mm bioresorbable plates

Requirement for additional (surgical) interventions (plate removal / re-operation) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement
1 finding from 1 review
  • Plate removal was statistically more likely in the titanium group (Fisher's exact P<0.05); infection led to plate removal in one titanium participant at 2 months and a further 4/21 (19%) titanium participants (six…
    1 study
    GRADE not reported

Locking plate vs 2 mm non-locking titanium plates

Requirement for additional (surgical) interventions · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement
1 finding from 1 review
  • Only Collins 2004 provided data: 6/122 participants had minor complications (three in each group); five required surgical removal of the locking plates and one post-operative malocclusion was managed with elastic…
    1 study · 122 participants
    GRADE not reported

Guided tissue regeneration (GTR) with barrier membrane (resorbable or non-resorbable) vs Open flap debridement (access flap surgery)

Treatment / surgical procedure time · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…

Guided tissue regeneration (GTR) with barrier membrane (resorbable… showed no clear difference in treatment / surgical procedure time compared with open flap debridement (access flap surgery); GRADE not reported.

1 finding from 1 review

Guided tissue regeneration (GTR) with barrier membrane (resorbable or non-resorbable) vs Open flap debridement (access flap surgery)

Hard tissue probing at surgical re-entry (bone gain) · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…

Guided tissue regeneration (GTR) with barrier membrane (resorbable… led to higher hard tissue probing at surgical re-entry (bone gain) compared with open flap debridement (access flap surgery); GRADE not reported.

1 finding from 1 review

GTR rm associated with bone substitutes vs Open flap debridement (access flap surgery)

Hard tissue probing at surgical re-entry (bone gain) · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…

Guided tissue regeneration (GTR) combined with bone substitutes/graft led to higher hard tissue probing at surgical re-entry (bone gain) compared with open flap debridement (access flap surgery); GRADE not reported.

1 finding from 1 review

Early loading of mini-screw implant vs Delayed loading of mini-screw implant

Success of the anchorage device · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

Early loading of mini-screw implant showed no clear difference in success of the anchorage device compared with delayed loading of mini-screw implant; GRADE not reported.

1 finding from 1 review

Dual mini-screw implant vs Single mini-screw implant

Residual overjet at the end of treatment · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

The review found no eligible studies for this question.

1 finding from 1 review

Dual mini-screw implant vs Single mini-screw implant

Success of the anchorage device · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

Dual mini-screw implant showed no clear difference in success of the anchorage device compared with single mini-screw implant; GRADE not reported.

1 finding from 1 review

Dual mini-screw implant vs Single mini-screw implant

Duration of space closure · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

Dual mini-screw implant showed no clear difference in duration of space closure compared with single mini-screw implant; GRADE not reported.

1 finding from 1 review

Pre-drilling mini-screw implant vs Self-drilling mini-screw implant

Success of the anchorage device · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

Pre-drilling mini-screw implant showed no clear difference in success of the anchorage device compared with self-drilling mini-screw implant; GRADE not reported.

1 finding from 1 review

Dual mini-screw implant vs Single mini-screw implant

Mesiodistal movement of the upper first permanent molar · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

Dual mini-screw implant led to higher mesiodistal movement of the upper first permanent molar compared with single mini-screw implant; GRADE not reported.

1 finding from 1 review

Pre-drilling mini-screw implant vs Self-drilling mini-screw implant

Patient perception: pain · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage
1 finding from 1 review

Ibuprofen (single postoperative oral dose; 200 mg to 512 mg) vs paracetamol

Participant‐reported pain relief of 50% or greater · Patients with pain after surgical removal of lower wisdom teeth (third molars) requiring bone removal or with baseline moderate to severe…

Ibuprofen (single postoperative oral dose; 200 mg to 512 mg) leads to higher proportion of patients with >50% maximum pain relief (TOTPAR) over 6… compared with paracetamol (acetaminophen) (single postoperative oral dose; 600 mg… (high certainty).

1 finding from 1 review