Findings

What do systematic reviews say?

142 questions · 149 findings · 12 reviews · Pain, Palliative and Supportive Care

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No studies found 44 · 29.5%GRADE not reported 15 · 10.1%Very low 34 · 22.8%Low 39 · 26.2%Moderate 14 · 9.4%High 3 · 2%

Nalbuphine vs morphine

Number of patients with moderate/severe pain (1 hour postoperatively) · children undergoing surgery

Nalbuphine showed no clear difference in number of patients with moderate/severe pain (1 hour postoperatively) compared with morphine (low certainty).

2 findings from 1 review

Nalbuphine for postoperative pain treatment in children 2014 · Cochrane Headline outcomes only
RR 0.84 [0.12, 5.74]
2 studies · 90 participants
Low
Nalbuphine for postoperative pain treatment in children 2014 · Cochrane Headline outcomes only
RR 1.09 [0.59, 2.01]
2 studies · 90 participants
Low

Nalbuphine vs morphine

Number of patients with the need for rescue analgesia (12 hours postoperatively) · children undergoing surgery

Nalbuphine showed no clear difference in number of patients with the need for rescue analgesia (12 hours… compared with morphine (low certainty).

1 finding from 1 review

Nalbuphine for postoperative pain treatment in children 2014 · Cochrane Headline outcomes only
RR 0.61 [0.37, 1.01]
1 study · 50 participants
Low