What do systematic reviews say?

Balloon sensory training biofeedback vs surgery

It is very uncertain whether balloon sensory training biofeedback changes number improved at one year compared with surgery (very low certainty).

• Biofeedback for treatment of chronic idiopathic constipation in adults 2014 · Cochrane Headline outcomes only
  RR 0.43 [0.21, 0.89]
  1 study · 40 participants
  Very low

Balloon sensory training biofeedback vs surgery

• Biofeedback for treatment of chronic idiopathic constipation in adults 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 40 participants
  Very low

Laparoscopic fundoplication vs medical management

• Laparoscopic fundoplication surgery versus medical management for gastro‐oesophageal reflux disease (GORD) in adults 2015 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 605 participants
  Very low

Laparoscopic fundoplication vs medical management

• Laparoscopic fundoplication surgery versus medical management for gastro‐oesophageal reflux disease (GORD) in adults 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 323 participants
  Very low

Laparoscopic fundoplication vs medical management

The review found no eligible studies for this question.

• Laparoscopic fundoplication surgery versus medical management for gastro‐oesophageal reflux disease (GORD) in adults 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Laparoscopic fundoplication vs medical management

It is very uncertain whether laparoscopic fundoplication changes serious adverse events compared with medical management (very low certainty).

• Laparoscopic fundoplication surgery versus medical management for gastro‐oesophageal reflux disease (GORD) in adults 2015 · Cochrane Headline outcomes only
  RR 1.46 [1.01, 2.11]
  2 studies · 637 participants
  Very low

Laparoscopic fundoplication vs medical management

The review found no eligible studies for this question.

• Laparoscopic fundoplication surgery versus medical management for gastro‐oesophageal reflux disease (GORD) in adults 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Laparoscopic fundoplication vs medical management

It is very uncertain whether laparoscopic fundoplication changes (5 years or more) compared with medical management (very low certainty).

• Laparoscopic fundoplication surgery versus medical management for gastro‐oesophageal reflux disease (GORD) in adults 2015 · Cochrane Headline outcomes only
  RR 0.9 [0.57, 1.42]
  1 study · 228 participants
  Very low

Laparoscopic fundoplication vs medical management

The review found no eligible studies for this question.

• Laparoscopic fundoplication surgery versus medical management for gastro‐oesophageal reflux disease (GORD) in adults 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Laparoscopic fundoplication vs medical management

The review found no eligible studies for this question.

• Laparoscopic fundoplication surgery versus medical management for gastro‐oesophageal reflux disease (GORD) in adults 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The intervention probably leads to lower lymph node mets analysis ‐ N+ OS (moderate certainty).

• Post‐surgical chemotherapy versus surgery alone for resectable gastric cancer 2013 · Cochrane Headline outcomes only
  HR 0.78 [0.67, 0.91]
  4 studies · 877 participants
  Moderate

Intervention not reported

The intervention probably leads to lower chemobased OS ‐ 5‐FU based chemotherapy OS (moderate certainty).

• Post‐surgical chemotherapy versus surgery alone for resectable gastric cancer 2013 · Cochrane Headline outcomes only
  HR 0.88 [0.83, 0.94]
  28 studies · 5694 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in chemobased OS ‐ Platinum‐based chemotherapy OS (moderate certainty).

• Post‐surgical chemotherapy versus surgery alone for resectable gastric cancer 2013 · Cochrane Headline outcomes only
  HR 0.9 [0.81, 1]
  9 studies · 1504 participants
  Moderate

Intervention not reported

The intervention probably leads to lower chemobased DFS ‐ 5‐FU based chemotherapy DFS (moderate certainty).

• Post‐surgical chemotherapy versus surgery alone for resectable gastric cancer 2013 · Cochrane Headline outcomes only
  HR 0.86 [0.78, 0.95]
  13 studies · 2944 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in chemobased DFS ‐ Platinum‐based chemotherapy DFS (moderate certainty).

• Post‐surgical chemotherapy versus surgery alone for resectable gastric cancer 2013 · Cochrane Headline outcomes only
  HR 0.89 [0.75, 1.06]
  4 studies · 969 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in stage OS analysis ‐ T1/2 OS (moderate certainty).

• Post‐surgical chemotherapy versus surgery alone for resectable gastric cancer 2013 · Cochrane Headline outcomes only
  HR 0.86 [0.71, 1.05]
  5 studies · 1146 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in stage OS analysis ‐ T3/4 OS (moderate certainty).

• Post‐surgical chemotherapy versus surgery alone for resectable gastric cancer 2013 · Cochrane Headline outcomes only
  HR 0.66 [0.41, 1.08]
  4 studies · 1008 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in lymph node mets analysis ‐ N‐ OS (moderate certainty).

• Post‐surgical chemotherapy versus surgery alone for resectable gastric cancer 2013 · Cochrane Headline outcomes only
  HR 0.74 [0.41, 1.33]
  2 studies · 402 participants
  Moderate